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Phenalenes

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Definition: A group of AROMATIC HYDROCARBONS that have three rings joined as a triad around a single carbon atom so all three are conjoined, in contrast to a linear arrangement (ANTHRACENES) or angular arrangement (PHENANTHRENES).     
Examples Perylene 		Other names Phenylphenalenones; Oxabenzochrysenones
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
4-hydroxy-3,3-dimethyl-2,3,7,8,9,9a-hexahydro-1H-phenalen-5-yl 6-deoxygalactopyranoside  0   *Galactosides *Phenalenes. Bioorg Med Chem 2010 Dec 1;18(23):8324-33
3-isopropyloxy-6-morpholino-2-phenylphenalen-1-one  0   *Morpholines *Phenalenes. Appl Biochem Biotechnol 2010 Mar;160(6):1744-51
haemodorose  0   *Phenalenes. J Nat Prod 2009 Jun;72(6):1075-80
haemodorol  0   *Phenalenes. J Nat Prod 2009 Jun;72(6):1075-80
haemodorone  0   *Phenalenes. J Nat Prod 2009 Jun;72(6):1075-80
9-demethyl FR-901235  0   *Phenalenes. Phytochemistry 2008 Mar;69(5):1273-8
monolaterol  0   *Phenalenes. J Nat Prod 2006 Nov;69(11):1614-7
bacillisporin E  0   *Phenalenes. Planta Med 2006 Aug;72(10):957-60
bacillisporin D  0   *Phenalenes. Planta Med 2006 Aug;72(10):957-60
2-hydroxy-8-(3,4-dihydroxyphenyl)-phenalen-1-one  0   *Phenalenes. Phytochemistry. 2005 Jan;66(1):59-64
2-hydroxy-8-(4-hydroxyphenyl)-phenalen-1-one  0   *Phenalenes. Phytochemistry. 2005 Jan;66(1):59-64
scriptide  0   *Hydroxamic Acids *Phenalenes Histone Deacetylases/antagonists & inhibitors. Biosci Biotechnol Biochem 2003 Jul;67(7):1499-506
6-O-((6''-O-allophanyl)glucopyranosyl)-5-hydroxy-2-methoxy-7-phenylphenalen-1-one  0   *Glucosides *Phenalenes. Planta 2003 Mar;216(5):881-9
anigorootin  0   *Phenalenes. Phytochemistry 2002 May;60(1):61-6
8-(2,3,3a,4,5,6-hexahydro-1H-phenalen-1-yl)-3-N-methyl-1-phenyl-1,3,8-triazaspiro(4.5)decan-4-one  0   *Imidazoles *Spiro Compounds *Phenalenes Carbon Radioisotopes. Nucl Med Biol 2001 Nov;28(8):941-7
2-amino-2,3,3a,4,5,6-hexahydro-1H-phenalene  0   *Amines *Phenalenes Receptors, Dopamine D2/antagonists & inhibitors. Farmaco 2000 Sep-Oct;55(9-10):575-82
8-(2,3,3a,4,5,6-hexahydro-1H-phenalen-1-yl)-1-phenyl-1,3,8-triaza-spiro(4.5)decan-4-one  0   *Aza Compounds *Spiro Compounds *Phenalenes. Eur J Med Chem 2000 Sep;35(9):839-51
N-(4-methoxy-2,3-dihydro-1H-phenalen-2-yl)acetamide  0   *Acetamides *Phenalenes. J Med Chem 1999 Mar 25;42(6):1100-5
barakol  24506-68-1   *Benzopyrans *Phenalenes. Eur J Pharmacol 1997 Jan 29;319(2-3):157-64; Pharm Biochem and Behavior 53(3):753-8 1996
U 67413B  0   *Phenalenes. J Pharmacol Exp Ther 1994 Mar;268(3):1304-10
rousselianone A  0   *Phenalenes. J Antibiot (Tokyo) 1993 Oct;46(10):1570-4
Org 33201  148714-92-5 1H-Imidazole, 1-((3a-ethyl-9-(ethylthio)-2,3,3a,4,5,6-hexahydro-1H-phenalen-2-yl)methyl)-, monohydrochloride, (2S-trans)  *Imidazoles *Phenalenes Aromatase Inhibitors. J Steroids Biochem Mol Biol 1993 Mar;44(4-6):681-2
U 65556A  112892-80-5   *Phenalenes. J Appl Toxicol 1990;10(6):401
U 64273A  33448-25-8   *Phenalenes. J Appl Toxicol 1990;10(6):401
2-dipropylamino-1-oxa-2,3-dihydro-1H-phenalene  132766-67-7   *Phenalenes. Drug Des Deliv 1990;6(3):177
2-dimethylamino-1-oxa-2,3-dihydro-1H-phenalene  132766-66-6   *Phenalenes. Drug Des Deliv 1990;6(3):177
alentamol  121514-27-0   *Phenalenes. J Pharmacol Exp Ther 1990;254(2):369
KB 5246  119474-55-4 3H,8H-4-Oxa-1-thia-9b-azacyclopenta(cd)phenalene-9-carboxylic acid, 6-fluoro-5-(4-methyl-1-piperazinyl)-8-oxo-, monohydrochloride  *Quinolones *Phenalenes. Antimicrob Agent Chemother 1989;33(11):1896
FR 901235  124190-19-8   *Phenalenes. J Antibiot (Tokyo) 1989;42(9):1356
2-methyl-1-oxo-1H-phenalene-3-acetic acid  118896-32-5   *Phenalenes Aldehyde Reductase/antagonists & inhibitors. J Med Chem 1989;32(4):757
phenalen-1-one  548-39-0   *Phenalenes. Anal Chem 1983;55(4):758
norherquienone  11023-93-1 3H-Phenaleno(1,2-b)furan-3,7(7aH)-dione, 8,9-dihydro-4,5,6,7a-tetrahydroxy-1,8,8,9-tetramethyl-, (7aS-cis)  *Phenalenes. Fortschr Chem Org Naturst 1981;40:153
herquienone  26871-30-7 3H-Phenaleno(1,2-b)furan-3,7(7aH)-dione, 8,9-dihydro-4,6,7a-trihydroxy-5-methoxy-1,8,8,9-tetramethyl-, (7aS-cis)  *Phenalenes. Fortschr Chem Org Naturst 1981;40:153
atrovenetin  2582-86-7 3H-Phenaleno(1,2-b)furan-3-one, 8,9-dihydro-4,5,6,7-tetrahydroxy-1,8,8,9-tetramethyl-, (R)  *Phenalenes. Fortschr Chem Org Naturst 1981;40:153
6,7-aceazuleno(5,6,7-cd)phenalene  0   *Phenalenes. Bull Soc Chim France 6:2514;1972
lachnanthocarpone  28241-21-6 2,6-dihydroxy-9-phenyl-1H-phenalen-1-one  *Phenalenes Pigments, Biological. Biochim Biophys Acta 286(1):88;1972

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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