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Rotaxanes

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Definition: Complex compounds in which a dumbbell shaped molecule is encircled by a macrocycle. They are named after rota (wheel) and axis (axle). Notation with a prefix is used to indicate the number of interlocked components. They have potential use in NANOTECHNOLOGY. Rotaxanes have been made with CYCLODEXTRINS and CYCLIC ETHERS.  coord with specific Cat D chemical structure term if pertinent; TAXANES is also available   
See Also Catenanes
Other names Rotaxane; Pseudorotaxanes; Polyrotaxanes
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
pseudopolyrotaxane  0   *Cyclodextrins *Poloxamer *Rotaxanes. Spectrochim Acta A Mol Biomol Spectrosc 2003 Jan 15;59(2):285-9
polyrotaxane  0   *Cyclodextrins *Poloxamer *Rotaxanes. Spectrochim Acta A Mol Biomol Spectrosc 2003 Jan 15;59(2):285-9

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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