encyclopedia of medical concepts
ψ 
ψ 

Receptor, Endothelin A

More information in Books or onNLM PubMed
Definition: A subtype of endothelin receptor found predominantly in the VASCULAR SMOOTH MUSCLE. It has a high affinity for ENDOTHELIN-1 and ENDOTHELIN-2.      Other names Receptors, Endothelin A; Receptor, Endothelin 1; Endothelin-1 Receptor; Endothelin A Receptor; Receptor, Endothelin-1; Endothelin A Receptors
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
DEspR protein, rat  0   *Receptors, Vascular Endothelial Growth Factor *Receptor, Endothelin A. Mol Imaging Biol. 2011 Dec;13(6):1096-106.
HJP 286  0   *Quinolones *Benzodioxoles Receptor, Endothelin A/antagonists & inhibitors. Am J Pathol 2010 Oct;177(4):1929-35
HJP 278  0   *Quinolones *Benzodioxoles Receptor, Endothelin A/antagonists & inhibitors. Am J Pathol 2010 Oct;177(4):1929-35
di-n-butylaminocarbamyl-leucyl-tryptophyl-4-chlorophenylalanine  0   *Oligopeptides Receptor, Endothelin A/antagonists & inhibitors. J Cardiovasc Pharmacol 2010 Sep;56(3):246-54
3-azabicyclo(3.2.1)octan-1-yl-leucyl-tryptophyl-4-chlorophenylalanine  0   *Oligopeptides *Azabicyclo Compounds Receptor, Endothelin A/antagonists & inhibitors. Pulm Pharmacol ther 2008 Oct;21(5):780-7
N-(5-(4-bromophenyl)-6-(2-(5-bromopyrimidin-2-yloxy)ethoxy)pyrimidin-4-yl)-N'-propylaminosulfonamide  0   *Pyrimidines *Sulfonamides Receptor, Endothelin A/antagonists & inhibitors Receptor, Endothelin B/antagonists & inhibitors. J Pharmacol Exp Ther 2008 Dec;327(3):736-45
2-(butyryl-(2'-(4-fluoro-5-methylisoxazol-3-ylsulfamoyl)biphenyl-4-ylmethyl)amino)-N-isopropyl-3-methylbutyramide  0   *Isoxazoles *Sulfonamides Receptors, Angiotensin/antagonists & inhibitors Receptor, Endothelin A/antagonists & inhibitors. Drug Metab Dispos 2007 May;35(5):795-805
2-(butyryl-(2'-(4-chloro-5-methylisoxazol-3-ylsulfamoyl)biphenyl-4-ylmethyl)amino)-N-isopropyl-3-methylbutyramide  0   *Isoxazoles *Sulfonamides Receptors, Angiotensin/antagonists & inhibitors Receptor, Endothelin A/antagonists & inhibitors. Drug Metab Dispos 2007 May;35(5):795-805
2-(butyryl-(2'-(4,5-dimethylisoxazol-3-ylsulfamoyl)biphenyl-4-ylmethyl)amino)-N-isopropyl-3-methylbutyramide  0   *Isoxazoles *Sulfonamides Receptors, Angiotensin/antagonists & inhibitors Receptor, Endothelin A/antagonists & inhibitors. Drug Metab Dispos 2007 May;35(5):795-805
N-(2-acetyl-4,6-dimethylphenyl)-3-(3,4-dimethylisoxazol-5-ylsulfamoyl)thiophene-2-carboxamide  0   *Isoxazoles *Sulfones Receptor, Endothelin A/antagonists & inhibitors. J Med Chem 2004 Apr 8;47(8):1969-86
clazosentan  180384-56-9 N-(6-(2-Hydroxyethoxy)-5-(2-methoxyphenoxy)-2-(2-(1H-tetrazol-5-yl)pyridin-4-yl)pyrimidin-4-yl)-5-methylpyridine-2-sulfonamide  *Dioxanes *Pyridines *Pyrimidines *Sulfonamides *Tetrazoles Vasospasm, Intracranial Receptor, Endothelin A. J Pharmacol Exp Ther 1997 Dec;283(3):1110-18

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy