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Receptors, Melatonin

More information in Books or onNLM PubMed
Definition: A family of G-protein-coupled receptors that are specific for and mediate the effects of MELATONIN. Activation of melatonin receptors has been associated with decreased intracellular CYCLIC AMP and increased hydrolysis of PHOSPHOINOSITIDES.  GEN or unspecified; prefer specifics    Other names Receptor, Mel1c; Melatonin MT3 Receptor; Mel(1c) Receptor; MT3 Receptor; Receptor, Melatonin MT3; Receptor, MT3; Melatonin Receptor; Mel1c Receptor; MT3 Receptor, Melatonin; Receptor, Melatonin, MT3; Receptor, Melatonin, 1C; Receptor, Melatonin; Melatonin Receptors
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
N-(2-(7-(cyclohexylmethyl)-1,6-dihydro-2H-indeno(5,4-b)furan-8-yl)ethyl)acetamide  0   *Acetamides *Benzofurans Receptors, Melatonin/agonists. J Med Chem 2011 May 12;54(9):3436-44
N-(2-(2-(4-phenylbutyl)benzofuran-4-yl)cyclopropylmethyl)acetamide  0   *Acetamides *Benzofurans Receptors, Melatonin/agonists. Bioorg Med Chem Lett 2004 Oct 18;14(20):5157-60
N-(8-methoxy-10,11-dihydro-5H-dibenzo(a,d)cycloheptene-10-ylmethyl)butyramide  0   *Dibenzocycloheptenes Polyunsaturated Alkamides Receptors, Melatonin/antagonists & inhibitors. J Med Chem 2004 Aug 12;47(17):4202-12
N-(8-methoxy-10,11-dihydro-5H-dibenzo(a,d)cycloheptene-10-ylmethyl)propionamide  0   *Dibenzocycloheptenes Polyunsaturated Alkamides Receptors, Melatonin/antagonists & inhibitors. J Med Chem 2004 Aug 12;47(17):4202-12
tasimelteon  0   *Benzofurans *Cyclopropanes Receptors, Melatonin/agonists. J Pharm Sci 2003 Apr;92(4):760-72

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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