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Holliday Junction Resolvases

More information in Books or onNLM PubMed
Definition: Enzymes that recognize CRUCIFORM DNA structures and introduce paired incisions that help to resolve the structure into two DNA helices.  do not confuse with TRANSPOSON RESOLVASES    Other names Endonuclease, Cruciform Cutting; Cruciform DNA Resolving Endonuclease; Resolvase, Holliday Junction; Cruciform Cutting Endonuclease; Resolvases, Holliday Junction; Holliday Junction Resolvase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Yen1 protein, S cerevisiae  EC 3.1.21.-   *Saccharomyces cerevisiae Proteins *Holliday Junction Resolvases. Nature. 2008 Nov 20;456(7220):357-61
GEN1 protein, human  EC 3.1.21.-   *Holliday Junction Resolvases. Nature 2008 Nov 20;456(7220):357-61
CCE1 protein, S cerevisiae  EC 3.1.21.-   *Saccharomyces cerevisiae Proteins *Holliday Junction Resolvases.
RusA protein, E coli  EC 3.1.21.-   *Escherichia coli Proteins *Holliday Junction Resolvases. Nucleic Acids Res 1998 Apr 1;26(7):1560-6

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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