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Tetraoxanes

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Definition: Compounds with two peroxide groups, that is, two pairs of adjacent OXYGEN atoms. They may have activity against PLASMODIUM similar to the ARTEMISININS.  coord with appropriate specific chemical terms if pertinent    Other names Tetra Oxanes; Tetroxanes; Tetra-Oxanes; 1,2,4,5-Tetraoxanes
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
RKA 182  0   *Spiro Compounds *Tetraoxanes. Angew Chem Int Ed Engl. 2010 Aug 2;49(33):5693-7
3,6-dibutanoic-1,2,4,5-tetroxane  0   *Tetraoxanes. Bioorg Med Chem. 2005 Oct 15;13(20):5826-9
3,6-diphenyl-1,2,4,5-tetroxane  0   *Tetraoxanes. ScientificWorldJournal 2002 Feb 15;2():455-60
dispiro-1,2,4,5-tetroxane  0   *Spiro Compounds *Tetraoxanes. Am J Trop Med Hyg 2000 May;62(5):573-8
1,10-bis(2-propenyl)-7,8,15,16-tetraoxadispiro(5.2.5.2)-hexadecane  0   *Alkanes *Spiro Compounds *Tetraoxanes. J Med Chem 1999 Apr 22;42(8):1477-80

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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