encyclopedia of medical concepts
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Proprotein Convertase 1

More information in Books or onNLM PubMed
Definition: A CALCIUM-dependent endopeptidase that has specificity for cleavage at ARGININE that is near paired basic residues. It cleaves a variety of prohormones including PRO-OPIOMELANOCORTIN; PRORENIN; proenkephalins; prodynorphin; prosomatostatin; and PROINSULIN.      Other names Prohormone Convertase, PC3; Endoprotease, PC3; Convertase, PC3 Prohormone; Convertase, PC1 Prohormone; Convertase SPC3, Proprotein; Convertase PC1, Neuroendocrine; Convertase 1, Proprotein; Proprotein Convertase SPC3; Proinsulin Convertase 1; Endoprotease, PC1; Prohormone Convertase, PC1; Prohormone Convertase 3; Prohormone Convertase 1; PC3 Prohormone Convertase; PC3 Endoprotease; PC1 Endoprotease; Neuroendocrine Convertase PC1; PC1 Prohormone Convertase
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Pcsk1 protein, mouse  EC 3.4.21.93   *Proprotein Convertase 1.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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