Eosinophil Major Basic Protein (definition)

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ψ	Eosinophil Major Basic Protein

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Definition: One of several basic proteins released from EOSINOPHIL cytoplasmic granules. Eosinophil major basic protein is a 14-kDa cytotoxic peptide with a pI of 10.9. In addition to its direct cytotoxic effects, it stimulates the release of variety of INFLAMMATION MEDIATORS.

Pharmacological Action Immunologic Factors

Other names Eosinophil MBP Protein; Basic Protein, Eosinophil; MBP Protein, Eosinophil; Major Basic Protein, Eosinophil; Eosinophil Basic Protein

Substance	CAS Registry & name	Categories	Source	Drugs*
Prg3 protein, mouse	0	*Eosinophil Major Basic Protein.
PRG2 protein, human	147016-17-9	Proteoglycans Eosinophil Major Basic Protein Protein Precursors.	Mol Immunol 1992 Apr;29(4):537-46

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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