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Eosinophil-Derived Neurotoxin

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Definition: A 19-kDa cationic peptide found in EOSINOPHIL granules. Eosinophil-derived neurotoxin is a RIBONUCLEASE and may play a role as an endogenous antiviral agent.     
Pharmacological Action Immunologic Factors 		Other names Neurotoxin, RNS2; Neurotoxin, Eosinophil-Derived; Eosinophil Derived Neurotoxin; Serum Eosinophil Protein X; RNS2 Neurotoxin; Eosinophil Protein X; s-EPX
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Ear2 protein, mouse  EC 3.1.-   *Eosinophil-Derived Neurotoxin. Circ Res. 2003 May 16;92(9):1033-40; Gene 2001 Apr 4;267(1):23-30
RNASE2 protein, human  EC 3.1.27.5   *Eosinophil-Derived Neurotoxin.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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