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Casein Kinase II

More information in Books or onNLM PubMed
Definition: A ubiquitous casein kinase that is comprised of two distinct catalytic subunits and dimeric regulatory subunit. Casein kinase II has been shown to phosphorylate a large number of substrates, many of which are proteins involved in the regulation of gene expression.      Other names Kinase CKII, Protein; Kinase 2alpha', Casein; 2alpha', Casein Kinase; Protein Kinase CKII; Protein Kinase CK2; Casein Kinase-2; Casein Kinase TS; Casein Kinase 2alpha'; Casein Kinase 2alpha; Casein Kinase 2 beta Subunit; Casein Kinase 2 alpha' Subunit; Casein Kinase 2 alpha Subunit; Casein Kinase 2
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
8-hydroxy-4-methyl-benzo(g)chromen-2-one  0   *Coumarins Casein Kinase II/antagonists & inhibitors. Cell Mol Life Sci. 2012 Feb;69(3):449-60.
8-hydroxy-4-methyl-9-nitrobenzo(g)chromen-2-one  0   *Coumarins Casein Kinase II/antagonists & inhibitors. Cell Mol Life Sci. 2012 Feb;69(3):449-60.
casein kinase 2, alpha, human  EC 2.7.11.1   Casein Kinase II Protein Isoforms. Mol Cell Biochem. 2011 Oct;356(1-2):57-65
3-(cyclopropylamino)-5-(3-(trifluoromethyl)phenylamino)pyrimido(4,5-c)quinoline-8-carboxylic acid  0   *Pyrimidines *Quinolines Casein Kinase II/antagonists & inhibitors. Biochemistry. 2011 Oct 4;50(39):8478-88.
5-(3-ethynylphenylamino)pyrimido(4,5-c)quinoline-8-carboxylic acid  0   *Pyrimidines *Quinolines Casein Kinase II/antagonists & inhibitors. Biochemistry. 2011 Oct 4;50(39):8478-88.
5-(3-chlorophenylamino)benzo(c)(2,6)naphthyridine-8-carboxylic acid  0   *Naphthyridines Casein Kinase II/antagonists & inhibitors. Cancer Res 2010 Dec 15;70(24):10288-98
3,8-dibromo-7-hydroxy-4-methylchromen-2-one  0   *Chromones Casein Kinase II/antagonists & inhibitors. J Med Chem 2008 Feb 28;51(4):752-9
Tc-1 protein, Trypanosoma cruzi  EC 2.7.1.37   *Casein Kinase II. Infect Immun 2006 Jul;74(7):3922-9
CKB4 protein, Arabidopsis  EC 2.7.1.37   *Arabidopsis Proteins *Casein Kinase II Protein Subunits. Plant J 2006 Jun;46(5):849-60
euchrestaflavanone B  0   *Flavanones Casein Kinase II/antagonists & inhibitors. Oncol Res 2005;15(6):327-32
casein kinase II, S pombe  EC 2.7.1.37   *Schizosaccharomyces pombe Proteins *Casein Kinase II.
casein kinase 2 beta (1-16)  0   *Peptide Fragments *Casein Kinase II. Biochem Biophys Res Commun 1997 Mar 6;232(1):178-82

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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