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Estrogen Receptor beta

More information in Books or onNLM PubMed
Definition: One of the ESTROGEN RECEPTORS that has greater affinity for ISOFLAVONES than ESTROGEN RECEPTOR ALPHA does. There is great sequence homology with ER alpha in the DNA-binding domain but not in the ligand binding and hinge domains.      Other names Receptor beta, Estrogen; Estrogen Receptors beta; Estrogen Receptor 2; ERbetacx; ERbeta
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
4-bromo-9a-butyl-7-hydroxy-1,2,9,9a-tetrahydro-3H-fluoren-3-one  0   *Fluorenes Estrogen Receptor beta/agonists. Bioorg Med Chem Lett 2006 Jul 1;16(13):3489-94
MF101 extract  0   *Plant Extracts Estrogen Receptor beta/agonists. Endocrinology 2007 Feb;14(2):538-47
8-(2,2-dimethylpropyl)naringenin  0   *Flavanones Estrogen Receptor beta/antagonists & inhibitors. J Med Chem 2006 Dec 14;49(25):7357-65
SERBA-1 compound  0   *Flavonoids Estrogen Receptor beta/agonists. J Med Chem 2006 Oct 19;49(21):6155-7
WAY 200070  0   *Oxazoles *Phenols Estrogen Receptor beta/agonists. Endocrinology 2005 Jul;146(7):3070-9
3-(3-fluoro-4-hydroxyphenyl)-7-hydroxy-1-naphthonitrile  0   *Naphthols Estrogen Receptor beta/agonists. J Med Chem 2005 Jun 16;48(12):3953-79
estrogen receptor beta isoform M, human  0   *Estrogen Receptor beta.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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