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Receptors, Tumor Necrosis Factor, Type II

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Definition: A tumor necrosis factor receptor subtype that is expressed primarily in IMMUNE SYSTEM cells. It has specificity for membrane-bound form of TUMOR NECROSIS FACTORS and mediates intracellular-signaling through TNF RECEPTOR ASSOCIATED FACTORS.      Other names Receptor, TNFRSF1B; Antigen, CD120b; Antigen, CD 120b; 120b Antigen, CD; Tumor Necrosis Factor Receptor Type 2; Tumor Necrosis Factor Receptor 75; Tumor Necrosis Factor Receptor 2; TNFRSF1B Receptor; TNFR2; TNFR p80; TNFR p75; TNF-sR75; TNF-RII; TNF-R75; TNF-R2; CD120b Antigen; CD 120b Antigen; Tumor Necrosis Factor Receptor Type II; Tumor Necrosis Factor Receptor Superfamily, Member; Receptors, Tumor Necrosis Factor, Member 1B
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
micp75TNFR protein, mouse  0   *Receptors, Tumor Necrosis Factor, Type II. Mol Immunol 2007 Jul;44(14):3563-70
TNFRSF1B protein, human  0   *Receptors, Tumor Necrosis Factor, Type II. Hum Mol Genet. 2000 Sep 1;9(14):2067-74

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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