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MAP Kinase Kinase 1

More information in Books or onNLM PubMed
Definition: An abundant 43-kDa mitogen-activated protein kinase kinase subtype with specificity for MITOGEN-ACTIVATED PROTEIN KINASE 1 and MITOGEN-ACTIVATED PROTEIN KINASE 3.      Other names Mitogen Activated Protein Kinase Kinase 1; MKK 1 Protein Kinase; MEK 1 Protein Kinase; Mitogen-Activated Protein Kinase Kinase 1; MKK1 Protein Kinase; MKK-1 Protein Kinase; MEK1 Protein Kinase; MEK-1 Protein Kinase; MAPK Kinase 1; MAP2K1 Protein
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
GSK 1120212  0   *Pyridones *Pyrimidinones MAP Kinase Kinase 1/antagonists & inhibitors MAP Kinase Kinase 2/antagonists & inhibitors. JOP 2011;12(2):114-6
MEK1 protein, zebrafish  EC 2.7.1.-   *Zebrafish Proteins *MAP Kinase Kinase 1. Infect Immun. 2010 Dec;78(12):5043-53
MEK1 protein, C elegans  EC 2.7.1.37   *Caenorhabditis elegans Proteins *MAP Kinase Kinase 1. Mol Cell Biol 1999 Aug;19(8):5523-34
pek-1 protein, C elegans  EC 2.7.10.-   *Cell Cycle Proteins *Caenorhabditis elegans Proteins *MAP Kinase Kinase 1.
Map2k1 protein, mouse  EC 2.7.1.-   *MAP Kinase Kinase 1.
MAP2K1 protein, human  EC 2.7.1.-   *MAP Kinase Kinase 1.
MEK1 protein, Arabidopsis  EC 2.7.1.-   *Arabidopsis Proteins *MAP Kinase Kinase 1. Plant Mol Biol 1997 Dec;35(6):1057-64
Mek1 protein, Nicotiana tabacum  EC 2.7.1.-   *Plant Proteins *MAP Kinase Kinase 1. J Biol Chem 2001 May 25;276(21):18139-45
Mek1 protein, S pombe  EC 2.7.10.-   *Cell Cycle Proteins *Schizosaccharomyces pombe Proteins *MAP Kinase Kinase 1. Nature 1999 Jun 3;399(6735):479-83

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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