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Proto-Oncogene Proteins B-raf

More information in Books or onNLM PubMed
Definition: A raf kinase subclass found at high levels in neuronal tissue. The B-raf Kinases are MAP kinase kinase kinases that have specificity for MAP KINASE KINASE 1 and MAP KINASE KINASE 2.      Other names Proto Oncogene Proteins B raf; Proto Oncogene Protein B raf; Proteins B-raf, Proto-Oncogene; Protein B-raf, Proto-Oncogene; B-raf, Proto-Oncogene Proteins; B-raf, Proto-Oncogene Protein; B raf Kinases; Proto-Oncogene Protein B-raf; BRAF Kinases; B-raf Kinases
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
7-(2,6-difluoro-4-(5-methyl-2,5-diazabicyclo(2.2.1)heptan-2-yl)phenyl)-3-(1H-indazol-4-yl)-2-(pyridin-4-yl)pyrazolo(1,5-a)pyrimidine  0   *Bicyclo Compounds, Heterocyclic Proto-Oncogene Proteins B-raf/antagonists & inhibitors. J Med Chem 2010 Nov 11;53(21):7874-8
2-(3,4,5-trimethoxyphenylamino)-6-(3-acetamidophenyl)pyrazine  0   *Acetanilides *Pyrazines Proto-Oncogene Proteins B-raf/antagonists & inhibitors. J Med Chem 2006 Jan 12;49(1):407-16
Braf protein, rat  EC 2.7.1.37   *Proto-Oncogene Proteins B-raf.
Braf protein, mouse  EC 2.7.1.37   *Proto-Oncogene Proteins B-raf.
BRAF protein, human  EC 2.7.1.37   *Proto-Oncogene Proteins B-raf.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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