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Receptors, Lysosphingolipid

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Definition: A subfamily of lysophospholipid receptors with specificity for LYSOSPHINGOLIPIDS such as sphingosine-1-phosphate and sphingosine phosphorylcholine.      Other names edg 8 Protein; edg 6 Receptor; edg 3 Protein; edg 1 Receptor; Sphingosine 1 Phosphate Receptors; Sphingosine 1 Phosphate Receptor; Receptors, Sphingosine-1-Phosphate; edg 1 Protein; Receptors, Sphingosine Phosphorylcholine; Receptors, Edg; Receptor, edg-6; Receptor, edg-1; Receptor, Sphingosine 1 Phosphate; Receptor, S1P5; Receptor, S1P4; Receptor, S1P3; Receptor, S1P2; Receptor, Nrg-1; Receptor, Edg-5; Protein, edg-8
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
sphingosine-1-phosphate receptor-2, rat  0   *Receptors, Lysosphingolipid. Hepatology. 2012 Jan;55(1):267-76
CS 0777  0   *Amino Alcohols *Pyrroles Receptors, Lysosphingolipid. J Clin Pharmacol. 2009 Jan;49(1):50-62.
spingosine-1-phosphate receptor 4, mouse  0   *Receptors, Lysosphingolipid. J Immunol. 2002 Oct 15;169(8):4084-7.
5-(3-(2-(2-hydroxy-1-(hydroxymethyl)ethyl)-5-methyl-1,2,3,4-tetrahydro-6-isoquinolinyl)-1,2,4-oxadiazol-5-yl)-2-((1-methylethyl)oxy)benzonitrile  0   *Isoquinolines *Oxadiazoles Receptors, Lysosphingolipid/agonists. J Med Chem. 2011 Oct 13;54(19):6724-33.
1-(hydroxymethyl)-3-(3-octylphenyl)cyclobutane  0   *Benzene Derivatives *Cyclobutanes Receptors, Lysosphingolipid/antagonists & inhibitors. J Pharmacol Exp Ther 2011 Sep;338(3):879-89
S1pr1 protein, mouse  0   *Receptors, Lysosphingolipid. J Bone Miner Metab. 2010 Nov;28(6):659-71
5-(3-chloro-4-(2,3-dihydroxy-propoxy)benzylidene)-2-propylimino-3-o-tolyl-thiazolidin-4-one  0   *Thiazoles Receptors, Lysosphingolipid/antagonists & inhibitors. J Med Chem 2010 May 27;53(10):4198-211
2-amino-2-(2-(2'-fluoro-4'-(4-methylphenylthio)biphenyl-4-yl)ethyl)propane-1,3-diol  0   *Biphenyl Compounds *Propanolamines Receptors, Lysosphingolipid/agonists. J Med Chem 2010 Apr 22;53(8):3154-68
sphingosine-1-phosphate receptor-2, mouse  0   *Receptors, Lysosphingolipid. Stroke 2008 Dec;39(12):3411-7
AUY 954  0   *Thiophenes beta-Alanine/*analogs & derivatives Receptors, Lysosphingolipid/agonists. Chem Biol 2006 Nov;13(11):1227-34
1-(4-((4-phenyl-5-trifluoromethyl-2-thienyl)methoxy)benzyl)azetidine-3-carboxylic acid  0   *Azetidines *Thiophenes Receptors, Lysosphingolipid/agonists. Drug Metab Dispos 2006 Aug;34(8):1367-75
3-amino-4-(3-hexylphenylamino)-4-oxobutylphosphonic acid  0   *Anilides *Phosphonic Acids Receptors, Lysosphingolipid/antagonists & inhibitors. Nat Chem Biol 2006 Aug;2(8):434-41
Edg3 protein, mouse  0   *Receptors, Lysosphingolipid. Circulation 2004 Nov 23;110(21):3355-9
S1PR2 protein, human  0   *Receptors, Lysosphingolipid. J Biol Chem 2003 Aug 29;278(35):32841-51
S1PR1 protein, human  0   *Receptors, Lysosphingolipid. Cancer Res. 2003 Aug 15;63(16):5151-8

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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