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TRPC Cation Channels

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Definition: A subgroup of TRP cation channels that contain 3-4 ANKYRIN repeats and a conserved C-terminal domain. Members are highly expressed in the CENTRAL NERVOUS SYSTEM. Selectivity for calcium over sodium ranges from 0.5 to 10.      Other names TRP Channel; Protein, TRP; Channels, TRPC Cation; Channel, TRP; Cation Channels, TRPC; Transient Receptor Potential Channels, Type C; TRP Protein
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
TRPC4AP protein, human  0   *TRPC Cation Channels. Genes Dev 2010 Jun 15;24(12):1236-41
TrpA1 protein, Drosophila  0   *Drosophila Proteins *TRPC Cation Channels. Nature 2008 Jul 10;454(7201):217-20
TRPC6 protein, zebrafish  0   *Zebrafish Proteins *TRPC Cation Channels. Gene Expr Patterns 2008 May;8(5):291-6
TRP-4 channel, C elegans  0   *Caenorhabditis elegans Proteins *TRPC Cation Channels. Nature. 2006 Mar 30;440(7084):684-7
Trpc5 protein, rat  0   *TRPC Cation Channels. J Neurosci 2005 Feb 2;25(5):1234-9
TRPC1 protein, Xenopus  0   *Xenopus Proteins *TRPC Cation Channels. Nat Neurosci 2005 Jun;8(6):730-5
Trpc7 protein, mouse  0   *TRPC Cation Channels.
TRPC7 protein, human  0   *TRPC Cation Channels.
Trpc7 protein, rat  0   *TRPC Cation Channels.
Trpc6 protein, mouse  0   *TRPC Cation Channels.
Trpc6 protein, rat  0   *TRPC Cation Channels.
TRPC2 protein, human  0   *TRPC Cation Channels.
Trpc2 protein, mouse  0   *TRPC Cation Channels.
Trpc2 protein, rat  0   *TRPC Cation Channels.
Tprc5 protein, rat  0   *TRPC Cation Channels.
TRPC5 protein, human  0   *TRPC Cation Channels.
TRPC4 ion channel  0   *TRPC Cation Channels.
Trpa1 protein, rat  0   *TRPC Cation Channels. Nature 2004 Jan 15;427(6971);260-5
TRPC6 protein, human  0   *TRPC Cation Channels. Nature 1999 Jan 21;397(6716):259-63; Oncogene 1999 Feb 18;18(7):1487-94
Trpc5 protein, mouse  0   *TRPC Cation Channels. J Biol Chem 1998 Apr 24;273(17):10279-87
TRPC3 cation channel  0   *TRPC Cation Channels. FEBS Lett 1997 Feb 10;403(1):83-6
transient receptor potential cation channel, subfamily C, member 1  0   *TRPC Cation Channels. FEBS Lett 1995 Oct 16;373(3):193-8; Proc Natl Acad Sci U S A 1995 Oct 10;92(21):9652-6

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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