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GABA Plasma Membrane Transport Proteins

More information in Books or onNLM PubMed
Definition: A family of plasma membrane neurotransmitter transporter proteins that regulates extracellular levels of the inhibitory neurotransmitter GAMMA-AMINOBUTYRIC ACID. They differ from GABA RECEPTORS, which signal cellular responses to GAMMA-AMINOBUTYRIC ACID. They control GABA reuptake into PRESYNAPTIC TERMINALS in the CENTRAL NERVOUS SYSTEM through high-affinity sodium-dependent transport.     
See Also GABA Modulators; Receptors, GABA
Other names Transporters, GABA-Specific Neurotransmitter; Transporters, GABA; Transporter, GAT2; Transporter, GAT-4; Transporter, GAT-2; Transporter 2, GABA; Neurotransmitter Transporters, GABA Specific; Neurotransmitter Transport Proteins, GABA Specific; Gamma Aminobutyric Acid Plasma Membrane Transport ; GAT 4 Transporter; GAT 3 Transporter; GAT 2 Transporter; GAT 1 Transporter; GABA-Specific Neurotransmitter Transporters; Gamma-Aminobutyric Acid Plasma Membrane Transport ; GAT3 Transporter; GAT2 Transporter; GAT1 Transporter; GAT-4 Transporter; GAT-3 Transporter
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Slc6a11 protein, mouse  0   *GABA Plasma Membrane Transport Proteins.
gabP protein, E coli  0   *Organic Anion Transporters *Escherichia coli Proteins *GABA Plasma Membrane Transport Proteins.
UGA4 protein, S cerevisiae  0   *Saccharomyces cerevisiae Proteins *GABA Plasma Membrane Transport Proteins.
Snf-11 protein, C elegans  0   *Caenorhabditis elegans Proteins *GABA Plasma Membrane Transport Proteins. Mol Biol Cell 2006 Jul;17(7):3021-30
Slc6a13 protein, mouse  0   *GABA Plasma Membrane Transport Proteins.
SLC6A13 protein, human  0   *GABA Plasma Membrane Transport Proteins.
Slc6a11 protein, rat  0   *GABA Plasma Membrane Transport Proteins.
SLC6A11 protein, human  0   *GABA Plasma Membrane Transport Proteins.
Slc6a1 protein, rat  0   *GABA Plasma Membrane Transport Proteins.
Slc6a1 protein, mouse  0   *GABA Plasma Membrane Transport Proteins.
SLC6A1 protein, human  0   *GABA Plasma Membrane Transport Proteins.
Slc6a12 protein, mouse  0   *GABA Plasma Membrane Transport Proteins.
GABA-beta-alanine transporter protein, Torpedo marmorata  0   *Fish Proteins *GABA Plasma Membrane Transport Proteins gamma-Aminobutyric Acid beta-Alanine. Eur J Biochem 1995 Dec 15;234(3):794-800
Gat2 protein, rat  0   *GABA Plasma Membrane Transport Proteins. Brain Res Mol Brain Res 1994 Oct;26(1-2):47-54
Gabt4 protein, mouse  0   *GABA Plasma Membrane Transport Proteins gamma-Aminobutyric Acid. J Biol Chem 1993 Jan 25;268(3):2106-12
betaine plasma membrane transport proteins  146313-33-9   *Carrier Proteins Betaine GABA Plasma Membrane Transport Proteins. J Biol Chem 1992;267(1):649

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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