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Organogold Compounds

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Definition: Organic compounds that contain GOLD as an integral part of the molecule. Some are used as ANTIRHEUMATIC AGENTS. The term chrysotherapy derives from an ancient Greek term for gold.     
See Also Gold Sodium Thiosulfate
Examples Aurothioglucose; Gold Sodium Thiomalate
Other names Compounds, Organogold
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
bromo(1,3-diethyl-4,5-bis(2-fluorophenyl)-1,3-dihydro-2H-imidazol-2-ylidene)gold(I)  0   *Organogold Compounds Thioredoxin-Disulfide Reductase/antagonists & inhibitors. J Med Chem. 2011 Dec 22;54(24):8605-15.
bis(cyanoethyl)phenylphosphine-Au(I)Cl  0   *Organogold Compounds. J Inorg Biochem. 2010 Mar;104(3):268-73
chlorido(cyclohexyldiphenylphosphine)gold(I)  0   *Organogold Compounds. Acta Crystallogr C. 2010 Mar;66(Pt 3):m55-7
(5,10,15-tris(N-methylpyridinium-4-yl)-20-(1-pyrenyl)-porphyrinato)gold(III)  0   *Metalloporphyrins *Organogold Compounds. J Biol Inorg Chem 2009 Sep;14(7):1037-52
chloro(diphenyl-2-pyridylphosphine)gold(I)  0   *Organogold Compounds Protein Tyrosine Phosphatases/antagonists & inhibitors. J Med Chem 2009 Nov 12;52(21):6912-8
tetrachloro(bis(3,5-dimethylpyrazolyl)methane)gold(III)  0   *Organogold Compounds. J Inorg Biochem 2009 Feb;103(2):190-4
(N-(N',N'-dimethylaminoethyl)-1,8-naphthalimide-4-sulfide)(triethylphosphine)gold(I)  0   *Organogold Compounds. J Med Chem 2009 Feb 12;52(3):763-70
(mu-2-naphthyl)bis((triphenylphosphine)gold(I))  0   *Organogold Compounds. Dalton Trans 2008 May 7;(17):2248-52
(2-naphthyl)(triphenylphosphine)gold(I)  0   *Organogold Compounds. Dalton Trans 2008 May 7;(17):2248-52
(Au(d2pypp)(2))Cl  0   *Phosphines *Organogold Compounds. Biochem Pharmacol 2007 Oct 1;74(7):992-1002
Au(TS)(PEt3)  0   *Organogold Compounds. Inorg Chem 2007 Aug 6;46(16):6236-8
dibromo(methyl N-(dithiocarboxy-kS,kS')-N-methylglicinato)gold(III)  0   *Organogold Compounds. Anticancer Drugs 2007 Mar;18(3):323-32
dichloro(methyl N-(dithiocarboxy-kS,kS')-N-methylglicinato)gold(III)  0   *Organogold Compounds. Anticancer Drugs 2007 Mar;18(3):323-32
diacetato(2-(1,1-dimethylbenzyl)pyridine)gold(III)  0   *Organogold Compounds. J Med Chem 2005 Oct 20;48(21):6761-56761-5
(6-(1,1-dimethylbenzyl)-2,2'-bipyridine)(2,6-xylidine)gold(III)  0   *Organogold Compounds. J Med Chem 2005 Oct 20;48(21):6761-5
dichloro(2-(dimethylaminomethyl)phenyl-C1,N)gold(III)  0   *Organogold Compounds. J Inorg Biochem. 2004 Jun;98(6):1009-16
chlorotriphenylphosphine-1,3-bis(diphenylphosphino)propanegold(I)  0   *Organogold Compounds. J Med Chem 2003 Apr 24;46(9):1737-42
tetrakis((trishydroxymethyl)phosphine)gold(I)  0   *Phosphines *Organogold Compounds. J Med Chem 2003 Mar 27;46(7):1130-2
hydroxo(6-(1,1-dimethylbenzyl)-2,2'-bipyridine)gold(III)  0   *Organogold Compounds 2,2'-Dipyridyl/*analogs & derivatives. J Med Chem 2002 Apr 1;45(8):1672-7
dihydroxo(bipyridine)gold(III)  0   *Organogold Compounds 2,2'-Dipyridyl/*analogs & derivatives. J Med Chem 2002 Apr 1;45(8):1672-7
chloro(triethylphosphine)gold(I)  0   *Organogold Compounds. J Inorg Biochem 2002 Jan 1;88(1):44-52
chlorobischolylglycinatogold(III)  0   *Organogold Compounds. J Inorg Biochem 2001 Apr;84(3-4):287-92
pyrazole(triphenylphosphine)gold(I)  0   *Organogold Compounds. J Inorg Biochem 2000 Mar;78(4):363-70
imidazole(triphenylphosphine)gold(I)  0   *Organogold Compounds. J Inorg Biochem 2000 Mar;78(4):363-70
chloro glycylhistidinate gold(III) complex  0   *Dipeptides *Organogold Compounds. Chem Biol Interact 2000 Feb 15;125(1):29-38
chloroquine(triphenylphosphine)gold(I)  0   *Organogold Compounds Chloroquine/*analogs & derivatives. J Med Chem 1997 Jun 6;40(12):1937-9
2-((dimethylamino)methyl)phenylgold(III) dichloride  91946-52-0   *Benzylamines *Organogold Compounds Gold. J Med Chem 1996 Dec 20;39(26):5208-14
triethylphosphine goldlupinylsulfide  0   *Quinazolines *Organogold Compounds Phosphines. Farmaco 1995 Sep;50(9):601-4
maleidoyl undecagold  0   *Organogold Compounds. J Struct Biol 1995 May-Jun;114(3):209-17
monomaleimido gold  0   *Maleimides *Organogold Compounds. Arch Biochem Biophys 1992 Nov 15;299(1):105-9
tris(dicyclohexylphenylphosphine)gold(I)  142225-28-3   *Organophosphorus Compounds *Organogold Compounds. Acta Crystallogr C 1992 May 15;48 ( Pt 5):915-7
chloro(dicyclohexylphenylphosphine)gold(I)  134535-05-0   *Organogold Compounds. Acta Crystallogr C 47(Pt 5):1072
8-thiotheophyllinate-triphenylphosphine gold(I)  137025-15-1   *Organophosphorus Compounds *Organogold Compounds Theophylline/*analogs & derivatives Gold. Anticancer Res 1991;11(2):625
bis(1,2-bis(diphenylphosphino)ethene)gold (I)  116449-44-6   *Organophosphorus Compounds *Organogold Compounds Gold. J Med Chem 1990;33(5):1386
bis(1,2-bis(diphenylphosphino)propane)gold (I)  116449-45-7   *Organophosphorus Compounds *Organogold Compounds Gold. J Med Chem 1990;33(5):1386
chlorobis(dicyclohexylphenylphosphine)gold(I)  117412-16-5 Gold, chlorobis(dicyclohexylphenylphosphine)  *Organogold Compounds. Acta Crystallogr C 1988;44(Pt 9):1659
(2-benzoxazolethiolato)(triphenylphosphine)gold(I)  59418-59-6   *Organogold Compounds Gold. Acta Crystallogr C 1989;45(Pt 9):1420
(N,N-bis(2-hydroxyethyl)dithiocarbamato-S,S')dichlorogold(III)  119251-62-6 Gold, (bis(2-hydroxyethyl)carbamodithioato-S,S')dichloro-, (SP-4-2)  *Organogold Compounds. Acta Crystallogr C 1988;44(Pt 12):2082
bis(1,2-bis(diphenylphosphino)ethane)gold(I)  47895-18-1   *Organophosphorus Compounds *Organogold Compounds Gold. Cancer Res 1986;46(11):5486
triethylphosphine gold nitrate  14243-51-7   *Organophosphorus Compounds *Organogold Compounds. J Inorg Biochem 1986;27(1):1
triethylphosphine gold bromide  14243-60-8 Gold, bromo(triethylphosphine)-, (T-4)  *Phosphines *Organogold Compounds. J Inorg Biochem 1984;21(1):21
undecagold  67954-30-7 Gold, tris(cyano-C)heptakis(4,4',4''-phosphinidynetris(benzenemethanamine)-P)undeca-, (31Au-Au)  *Organogold Compounds. Science 1982;218(4569):290
bis(triethylphosphine)gold chloride  65583-79-1   *Organophosphorus Compounds *Organogold Compounds Gold. Biochem Soc Trans 7(4):731;1979
bis(L-cysteinato)gold(I)  71547-19-8 Aurate(3-), bis(L-cysteinato(2-)-N,S)-, trihydrogen  *Organogold Compounds Cysteine/*analogs & derivatives. J Inorg Biochem 10(4):317;1979
triphenylphosphine gold chloride  14243-64-2 chloro(triphenylphosphine)gold  *Organogold Compounds. Arthritis Rheum 21(4):441;1978
triethyl phosphine gold  15529-90-5 chloro(triethylphosphine)gold  *Phosphines *Organogold Compounds Gold. Agents Actions 8(5):546;1978; Arthritis Rheum 21(4):441;1978; Biochem Soc Trans 7(4):731;1979; J Pharmacol 181(2):292;1972; Vet Pathol 15(Suppl 5):1;1978; Vet Pathol 15(Suppl 5):13;1978; Vet Pathol 15(Suppl 5):9;1978; Vet Pathol 15(Suppl 5):97;1978; Virchows Archiv (Cell Pathol) 26(2):105;1977
aurotioprol  27279-43-2   *Organogold Compounds Sulfhydryl Compounds Propanols.
Pharma Action Antirheumatic Agents
Ann Med Intern 127(8-9):552;1976; Lille Med 22(7):430;1977; Schweiz Med Wochenschr 108(49):1969;1978; Ter Arkh 1980;52(2):102

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

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