Definition: A negative regulator of the CELL CYCLE that undergoes PHOSPHORYLATION by CYCLIN-DEPENDENT KINASES. It contains a conserved pocket region that binds E2F4 TRANSCRIPTION FACTOR and interacts with viral ONCOPROTEINS such as POLYOMAVIRUS TUMOR ANTIGENS; ADENOVIRUS E1A PROTEINS; and PAPILLOMAVIRUS E7 PROTEINS.
Other names p107, Retinoblastoma-Like Protein; Retinoblastoma Like Protein 1; p107 Tumor Suppressor Protein; Retinoblastoma Like Protein p107; RBL1 Protein; Retinoblastoma-Like Protein 1