Hepatocyte Nuclear Factors (definition)

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Hepatocyte Nuclear Factors

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Definition: Hepatocyte nuclear factors are a family of evolutionarily conserved transcription factors that are preferentially expressed in HEPATOCYTES. They play important roles in liver-specific transcription and are critical for CELL DIFFERENTIATION and METABOLISM.

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Examples Hepatocyte Nuclear Factor 1; Hepatocyte Nuclear Factor 3-alpha; Hepatocyte Nuclear Factor 3-beta; Hepatocyte Nuclear Factor 3-gamma; Hepatocyte Nuclear Factor 4; Hepatocyte Nuclear Factor 6

Substance	CAS Registry & name	Categories	Source	Drugs*
HNF-3 protein, Branchiostoma floridae	0	Nerve Tissue Proteins Hepatocyte Nuclear Factors *Forkhead Transcription Factors.	Dev Biol 1997 Mar 1;183(1):74-85

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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