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Cyclooxygenase 1

More information in Books or onNLM PubMed
Definition: A constitutively-expressed subtype of prostaglandin-endoperoxide synthase. It plays an important role in many cellular processes.      Other names Synthase, COX-1 Prostaglandin; Prostaglandin Synthase, COX-1; Prostaglandin H Synthase 1; Cyclo Oxygenase I; COX 1 Prostaglandin Synthase; Cyclooxygenase-1; Cyclo-Oxygenase I; COX-1 Prostaglandin Synthase; Prostaglandin H Synthase-1
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
3-methoxy-1,5-bis(4-methoxyphenyl)-1H-1,2,4-triazole  0   *Triazoles Cyclooxygenase Inhibitors Cyclooxygenase 1. Biochem Pharmacol 2011 Oct 1;82(7):746-54
ethyl 4-(benzyloxy)-3-((3-(4-methoxytetrahydro-2H-pyran-4-yl)phenyl)methylsulfonamido)benzoate  0   *Benzoates *Sulfonamides Lipoxygenase Inhibitors Cyclooxygenase Inhibitors Cyclooxygenase 1 Cyclooxygenase 2 Inhibitors. Bioorg Med Chem 2011 Mar 15;19(6):2074-83
N-(5-amino-2-pyridinyl)-4-trifluoromethylbenzamide  0   *Aminopyridines *Benzamides Cyclooxygenase 1. J Med Chem 2008 Apr 24;51(8):2400-11
2-(4-aminophenyl)-3-(3,5-dihydroxylphenyl)propenoic acid  0   *Aniline Compounds *Caffeic Acids Arachidonate 5-Lipoxygenase/antagonists & inhibitors Cyclooxygenase 1 Cyclooxygenase 2. Basic Clin Pharmacol Toxicol 2009 Nov;105(5):350-6
Ptgs1 protein, rat  EC 1.14.99.1   *Membrane Proteins *Cyclooxygenase 1.
Ptgs1 protein, mouse  EC 1.14.99.1   *Membrane Proteins *Cyclooxygenase 1.
PTGS1 protein, human  EC 1.14.99.1   *Cyclooxygenase 1.
mofezolac  78967-07-4   *Isoxazoles Cyclooxygenase 1.
Pharma Action Cyclooxygenase Inhibitors 		J Chromatogr 1987;422:227

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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