Complement C5 Convertase (definition)

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ψ	Complement C5 Convertase, Classical Pathway

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Definition: A serine protease that cleaves multiple COMPLEMENT 5 into COMPLEMENT 5A (anaphylatoxin) and COMPLEMENT 5B in the CLASSICAL COMPLEMENT ACTIVATION PATHWAY. It is a complex of CLASSICAL PATHWAY C3 CONVERTASE (C4b2a) with an additional COMPLEMENT C3B, or C4b2a3b.

Pharmacological Action Immunologic Factors

Other names C5 Convertase, Classical; Classical Pathway C5 Convertase; Classical C5 Convertase; C5 Convertase (C4b2a3b)

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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Complement C5 Convertase, Classical Pathway