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X-Linked Inhibitor of Apoptosis Protein

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Definition: An inhibitor of apoptosis protein that is translated by a rare cap-independent mechanism. It blocks caspase-mediated cellular destruction by inhibiting CASPASE 3; CASPASE 7; and CASPASE 9.      Other names X Linked Inhibitor of Apoptosis Protein; X Linked IAP Protein; IAP Protein, X-Linked; X-Linked IAP Protein; XIAP Protein
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
6-(2-(methylamino)propanamido)-5-oxo-9-(2-phenylacetamido)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)decahydropyrrolo(1,2-a)azocine-3-carboxamide  0   *Bicyclo Compounds, Heterocyclic Alanine/*analogs & derivatives Inhibitor of Apoptosis Proteins/antagonists & inhibitors X-Linked Inhibitor of Apoptosis Protein/antagonists & inhibitors. J Med Chem 2010 Sep 9;53(17):6361-7
XIAP protein, human  0   *X-Linked Inhibitor of Apoptosis Protein.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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