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Basic Helix-Loop-Helix Transcription Factors

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Definition: A family of DNA-binding transcription factors that contain a basic HELIX-LOOP-HELIX MOTIF.     
See Also Helix-Loop-Helix Motifs
Examples ARNTL Transcription Factors; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; CLOCK Proteins; Hypoxia-Inducible Factor 1; Myogenic Regulatory Factors; Twist Transcription Factor; Upstream Stimulatory Factors 		Other names Transcription Factors, bHLH; Basic Helix Loop Helix Transcription Factors; bHLH Transcription Factors; bHLH Proteins
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
BHLHA9 protein, human  0   *Basic Helix-Loop-Helix Transcription Factors Helix-Loop-Helix Motifs. J Med Genet. 2012 Feb;49(2):119-25
musculin protein, zebrafish  0   *Zebrafish Proteins *Basic Helix-Loop-Helix Transcription Factors. Cell Mol Life Sci. 2011 Dec;68(24):4065-78
Hes6 protein, rat  0   *Basic Helix-Loop-Helix Transcription Factors. Brain Res. 2010 Feb 8;1313:1-8.
HLH-16 protein, C elegans  0   *Caenorhabditis elegans Proteins *Basic Helix-Loop-Helix Transcription Factors. Curr Biol. 2011 Jul 26;21(14):1225-31.
HAF protein, Arabidopsis  0   *Arabidopsis Proteins *Basic Helix-Loop-Helix Transcription Factors. Development 2011 Jul;138(14):2999-3009
oligodendrocyte lineage transcription factor 3, human  0   *Basic Helix-Loop-Helix Transcription Factors. Nat Protoc 2011 May;6(5):640-55
MIST1 protein, human  0   *Basic Helix-Loop-Helix Transcription Factors. Dev Biol 1997 Feb 1;182(1):101-13
NGN-1 protein, C elegans  0   *Caenorhabditis elegans Proteins *Basic Helix-Loop-Helix Transcription Factors Nerve Tissue Proteins.
UPBEAT1 protein, Arabidopsis  0   *Arabidopsis Proteins *Basic Helix-Loop-Helix Transcription Factors. Cell 2010 Nov 12;143(4):606-16
SOHLH1 protein, human  0   *Basic Helix-Loop-Helix Transcription Factors. Proc Natl Acad Sci U S A 2006 May 23;103(21):8090-5
TMO7 protein, Arabidopsis  0   *Arabidopsis Proteins *Basic Helix-Loop-Helix Transcription Factors. Nature. 2010 Apr 8;464(7290):913-6
TARGET OF MP 5 protein, Arabidopsis  0   *Arabidopsis Proteins *Basic Helix-Loop-Helix Transcription Factors. Nature. 2010 Apr 8;464(7290):913-6
RSL4 protein, Arabidopsis  0   *Arabidopsis Proteins *Basic Helix-Loop-Helix Transcription Factors. Nat Genet 2010 Mar;42(3):264-7
HLH-11 protein, Arabidopsis  0   *Arabidopsis Proteins *Basic Helix-Loop-Helix Transcription Factors. Mol Cells 2009 Nov;28(5):455-61
bHLH92 protein, Arabidopsis  0   *Arabidopsis Proteins *Basic Helix-Loop-Helix Transcription Factors. Mol Genet Genomics. 2009 Nov;282(5):503-16
Sim1 protein, rat  0   *Repressor Proteins *Basic Helix-Loop-Helix Transcription Factors Helix-Loop-Helix Motifs. Obesity (Silver Spring). 2009 Jul;17(7):1356-62
HLH-13 protein, C elegans  0   *Caenorhabditis elegans Proteins *Basic Helix-Loop-Helix Transcription Factors. Dev Biol 2009 Mar 1;327(1):97-105
Fad24 protein, zebrafish  0   *Zebrafish Proteins *Basic Helix-Loop-Helix Transcription Factors Membrane Proteins. Dev Dyn 2009 Jan;238(1):86-99
FIGLA protein, human  0   *Basic Helix-Loop-Helix Transcription Factors. Mol Cell Endocrinol 2008 Jul 16;289(1-2):10-5
ICE2 protein, Arabidopsis  0   *Arabidopsis Proteins *Basic Helix-Loop-Helix Transcription Factors. Gene 2009 Jan 15;429(1-2):98-103
Ngn2 protein, rat  0   *Nerve Tissue Proteins *Basic Helix-Loop-Helix Transcription Factors. Mol Ther 2008 Nov;16(11):1873-82
pMesogenin2 protein, Xenopus  0   *Xenopus Proteins *Basic Helix-Loop-Helix Transcription Factors. Dev Dyn 2008 Dec;237(12):3749-61
pMesogenin1 protein, Xenopus  0   *Xenopus Proteins *Basic Helix-Loop-Helix Transcription Factors. Dev Dyn 2008 Dec;237(12):3749-61
CIB1 protein, Arabidopsis  0   *Arabidopsis Proteins *Basic Helix-Loop-Helix Transcription Factors. Science. 2008 Dec 5;322(5907):1535-9
Npas4 protein, mouse  0   *Basic Helix-Loop-Helix Transcription Factors. Nature 2008 Oct 30;455(7217):1198-204
RETARDED GROWTH OF EMBRYO1 protein, Arabidopsis  0   *Arabidopsis Proteins *Basic Helix-Loop-Helix Transcription Factors. Plant Physiol 2008 Aug;147(4):1924-35
Mespb protein, Xenopus  0   *Xenopus Proteins *Basic Helix-Loop-Helix Transcription Factors. Dev Biol 2008 Mar 15;315(2):317-30
Twist1 protein, zebrafish  0   *Zebrafish Proteins *Basic Helix-Loop-Helix Transcription Factors. Dev Genes Evol 2007 Dec;217(11-12):783-9
AIB protein, Arabidopsis  0   *Arabidopsis Proteins *Basic Helix-Loop-Helix Transcription Factors. Plant Mol Biol 2007 Nov;65(5):655-65
bHLH048 protein, Arabidopsis  0   *Arabidopsis Proteins *Basic Helix-Loop-Helix Transcription Factors. Nucleic Acids Res 2007;35(19):6663-71
PAR2 protein, Arabidopsis  0   *Arabidopsis Proteins *Basic Helix-Loop-Helix Transcription Factors Helix-Loop-Helix Motifs. EMBO J 2007 Nov 14;26(22):4756-67
PAR1 protein, Arabidopsis  0   *Arabidopsis Proteins *Basic Helix-Loop-Helix Transcription Factors Helix-Loop-Helix Motifs. Plant Physiol 2006 May;141(1):85-96
Olig2 protein, rat  0   *Nerve Tissue Proteins *Basic Helix-Loop-Helix Transcription Factors. J Biol Chem 2007 Jul 6;282(27):19700-9
bHLH39 protein, Arabidopsis  0   *Arabidopsis Proteins *Basic Helix-Loop-Helix Transcription Factors. Planta 2007 Jun;226(1):147-58
bHLH38 protein, Arabidopsis  0   *Arabidopsis Proteins *Basic Helix-Loop-Helix Transcription Factors. Planta 2007 Jun;226(1):147-58
RSL1 protein, Arabidopsis  0   *Arabidopsis Proteins *Basic Helix-Loop-Helix Transcription Factors. Science 2007 Jun 8;316(5830):1477-80
RHD6 protein, Arabidopsis  0   *Arabidopsis Proteins *Basic Helix-Loop-Helix Transcription Factors. Science 2007 Jun 8;316(5830):1477-80
HLH-29 protein, C elegans  0   *Caenorhabditis elegans Proteins *Basic Helix-Loop-Helix Transcription Factors. Biochim Biophys Acta 2007 Jan;1769(1):5-19
HLH-28 protein, C elegans  0   *Caenorhabditis elegans Proteins *Basic Helix-Loop-Helix Transcription Factors. Biochim Biophys Acta 2007 Jan;1769(1):5-19
TFPT protein, mouse  0   *Basic Helix-Loop-Helix Transcription Factors. Apoptosis 2006 Dec;11(12):2217-24
HLH-6 protein, C elegans  0   *Caenorhabditis elegans Proteins *Basic Helix-Loop-Helix Transcription Factors. Dev Biol 2007 Feb 1;302(1):295-308
FAMA protein, Arabidopsis  0   *Arabidopsis Proteins *Basic Helix-Loop-Helix Transcription Factors. Nature. 2007 Feb 1;445(7127):501-5
SPEECHLESS protein, Arabidopsis  0   *Arabidopsis Proteins *Basic Helix-Loop-Helix Transcription Factors. Nature. 2007 Feb 1;445(7127):501-5
MUTE protein, Arabidopsis  0   *Arabidopsis Proteins *Basic Helix-Loop-Helix Transcription Factors. Nature. 2007 Feb 1;445(7127):501-5
HND-1 protein, C elegans  0   *Caenorhabditis elegans Proteins *Basic Helix-Loop-Helix Transcription Factors. Genes Dev 2006 Dec 15;20(24):3342-6
Npas4 protein, rat  0   *Basic Helix-Loop-Helix Transcription Factors Helix-Loop-Helix Motifs. Eur J Neurosci. 2006 Nov;24(10):2705-20
Dec2 protein, zebrafish  0   *Zebrafish Proteins *Basic Helix-Loop-Helix Transcription Factors. Biochem Biophys Res Commun 2006 Dec 29;351(4):1072-7
Dec1 protein, zebrafish  0   *Zebrafish Proteins *Basic Helix-Loop-Helix Transcription Factors Circadian Rhythm. Gene Expr Patterns 2006 Oct;6(8):919-27
Hes2 protein, Xenopus  0   *Xenopus Proteins *Basic Helix-Loop-Helix Transcription Factors Repressor Proteins. Development 2006 Oct;133(20):4097-108
SAC51 protein, Arabidopsis  0   *Arabidopsis Proteins *Basic Helix-Loop-Helix Transcription Factors. Development 2006 Sep;133(18):3575-85
Sohlh2 protein, mouse  0   *Basic Helix-Loop-Helix Transcription Factors. Gene Expr Patterns 2006 Oct;6(8):1014-8
DYT1 protein, Arabidopsis  0   *Arabidopsis Proteins *Basic Helix-Loop-Helix Transcription Factors. Development 2006 Aug;133(16):3085-95
BIGPETAL protein, Arabidopsis  0   *Arabidopsis Proteins *Basic Helix-Loop-Helix Transcription Factors. EMBO J 2006 Aug 23;25(16):3912-20
dysfusion protein, Drosophila  0   *Drosophila Proteins *Basic Helix-Loop-Helix Transcription Factors. Mol Cell Biol 2003 Aug;23(16):5625-37
TCF15 protein, human  0   *Basic Helix-Loop-Helix Transcription Factors Helix-Loop-Helix Motifs.
Mxi1 protein, rat  0   *Tumor Suppressor Proteins *Basic Helix-Loop-Helix Transcription Factors.
Mxi1 protein, mouse  0   *Tumor Suppressor Proteins *Basic Helix-Loop-Helix Transcription Factors.
Olig2 protein, mouse  0   *Nerve Tissue Proteins *Basic Helix-Loop-Helix Transcription Factors.
Npas1 protein, mouse  0   *Nerve Tissue Proteins *Basic Helix-Loop-Helix Transcription Factors.
AIG1 protein, Arabidopsis  0   *Arabidopsis Proteins *Basic Helix-Loop-Helix Transcription Factors Helix-Loop-Helix Motifs. Biochim Biophys Acta 2006 Mar-Apr;1759(3-4):191-4
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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