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Fas Ligand Protein

More information in Books or onNLM PubMed
Definition: A transmembrane protein belonging to the tumor necrosis factor superfamily that was originally discovered on cells of the lymphoid-myeloid lineage, including activated T-LYMPHOCYTES and NATURAL KILLER CELLS. It plays an important role in immune homeostasis and cell-mediated toxicity by binding to the FAS RECEPTOR and triggering APOPTOSIS.      Other names Antigen, CD178; TNF Superfamily, Member 6; FasL Protein; Fas Ligand (FasL); Fas Ligand; CD95L; CD95 Antigen Ligand; CD178 Antigen; CD95 Ligand; Tumor Necrosis Factor Ligand Superfamily Member 6; CD178 Antigens; Antigens, CD178
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Tnfsf6 protein, rat  0   *Fas Ligand Protein.
FASLG protein, human  0   *Fas Ligand Protein.
Fasl protein, mouse  0   *Fas Ligand Protein.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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