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RANK Ligand

More information in Books or onNLM PubMed
Definition: A transmembrane protein belonging to the tumor necrosis factor superfamily that specifically binds RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B and OSTEOPROTEGERIN. It plays an important role in regulating OSTEOCLAST differentiation and activation.      Other names Tumor Necrosis Factor Related Activation Induced C; Receptor Activator of Nuclear Factor kappaB Ligand; Receptor Activator of Nuclear Factor kappa B Ligan; Differentiation Factor, Osteoclast; Tumor Necrosis Factor-Related Activation-Induced C; TRANCE Protein; TNF Superfamily, Member 11; Receptor Activator of Nuclear Factor-kappaB Ligand; Receptor Activator of Nuclear Factor-kappa B Ligan; RANKL Protein; Osteoprotegerin Ligand; Osteoclast Differentiation Factor; OPGL Protein; Tumor Necrosis Factor Ligand Superfamily Member 11
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Tnfsf11 protein, mouse  0   *RANK Ligand.
TNFSF11 protein, human  0   *RANK Ligand.
denosumab  615258-40-7   *Antibodies, Monoclonal RANK Ligand/antagonists & inhibitors. J Bone Miner Res 2004 Jul;19(7);1059-66PROLIA; XGEVA

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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