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Diynes

More information in Books or onNLM PubMed
Definition: Compounds with two triple bonds. Some of them are CYTOTOXINS.     
Examples Enediynes
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
(6E,12Z)-tetradecadiene-8,10-diyne-1,3-diol  0   *Fatty Alcohols *Diynes Stereoisomerism. J Asian Nat Prod Res. 2011 Apr;13(4):346-9
exocarpic acid  0   *Fatty Acids, Unsaturated *Diynes. Planta Med. 2009 Oct;75(12):1326-30
indoleacetic acid falcarindiol ester  0   *Diynes *Fatty Alcohols *Indoleacetic Acids. Planta Med 2009 Jan;75(1):49-54
dodeca-2Z,4E-diene-8,10-diynoic acid isobutylamide  0   *Amides *Fatty Acids, Unsaturated *Diynes. J Nat Prod 2005 May;68(5):773-6
(9R,10S)-epoxy-16-heptadecene-4, 6-diyne-3-one  0   *Epoxy Compounds *Diynes. J Agric Food Chem. 2005 Feb 23;53(4):919-22
heneicosa-10,12-diynoic acid  0   *Fatty Acids, Unsaturated *Diynes. Biofizika. 2004 Jul-Aug;49(4):635-45
panaxydiol  0   *Diynes. Chem Pharm Bull (Tokyo) 2004 Apr;52(4):418-21
1,6-bis(4,7-diaza-6-methyl-5-oxo-3-((2-((5-(phenylthio)tetrazol-1-yl)methyl)pyrrolidin-1-yl)carbonyl)octyloxy)-2,4-hexadiyne  0   *Tetrazoles *Diynes Apoptosis. Science 2004 Sep 3;305(5689):1471-4
(3S,18S,4E,16E)-eicosa-1,19-diyne-3,18-diol-4,16-diene  0   *Diynes. J Nat Prod 2003 Jun;66(6):871-2
spiroketalenol ether-6,7-epoxy-diyne  0   *Epoxy Compounds *Diynes. Phytochemistry 2002 Dec;61(8):913-7
10-chloro-1-heptadecene-4,6-diyne-3,8,9-triol  0   *Diynes. Chem Pharm Bull (Tokyo) 2002 Jan;50(1):115-7
13,14-dihydrooropheic acid  0 13(E),17-octadecadiene-9,11-diynoic acid  *Carboxylic Acids *Diynes. J Nat Prod 2001 Oct;64(10):1348-9
1-(2-furyl)pentacosa-16,18-diyne  0   *Furans *Diynes. Planta Med 2001 Aug;67(6):572-5
23-(2-furyl)tricosa-5,7-diynoic acid  0   *Furans *Diynes. Planta Med 2001 Aug;67(6):572-5
16-hydroxy-9,17-octadecadiene-12,14-diynoic acid  0   *Fatty Acids, Unsaturated *Diynes Allergens. Contact Dermatitis 1999 Apr;40(4):209-13
1,10-heptadecadiene-4,6-diyne-3,8,9-triol  0   *Fatty Alcohols *Diynes. Planta Med 1996 Jun;62(3):256-9
1,9-heptadecadiene-4,6-diyne-3,8,11-triol  0   *Fatty Alcohols *Diynes. Planta Med 1996 Jun;62(3):256-9
santolindiacetylene  0   *Naphthalenes *Diynes. J Nat Prod 1995 Nov;58(11):1749-52
1,9,16-heptadecatriene-4,6-diyne-3,8-diol  63898-22-6   *Fatty Alcohols *Diynes. Planta Med 1995 Oct;61(5):470-1
11-oxooctadeca-9,12-diynoic acid  0   *Fatty Acids, Unsaturated *Diynes. Biochemistry 1995 Aug 22;34(33):10538-45
octadeca-9,12-diynoic acid  0   *Fatty Acids, Unsaturated *Diynes. Biochemistry 1995 Aug 22;34(33):10538-45
tetradecadiene-8,10-diyne-1,3-diol diacetate  0   *Fatty Alcohols *Diynes Xanthine Oxidase/antagonists & inhibitors. Biol Pharm Bull 1994 Oct;17(10):1364-8
1,6-diphenyl-3-hexene-1,5,-diyne  27370-85-0   *Diynes. J Photochem Photobiol B 1993 Dec;21(2-3):135-42
1,2-bis(15-oxapentacosa-10,12-diynoyl)-sn-phosphocholine  148077-85-4   *Phosphatidylcholines *Diynes. Chem Phys Lipids 1992 Dec;63(3):191-201
1,2-bis(9,16-dioxahexacosa-11,13-diynoyl)-sn-3-phosphocholine  148057-01-6   *Phosphatidylcholines *Diynes. Chem Phys Lipids 1992 Dec;63(3):191-201
xerulinic acid  132971-62-1 2,8,10,12-Tetradecatetraene-4,6-diynoic acid, 14-(5-oxo-2(5H)-furanylidene)-, (Z,E,E,E,E)  *Lactones *Diynes. J Antibiot (Tokyo) 1990;43(11):1413
capillin  495-74-9   *Diynes Plant Extracts. Indian J Exp Biol 1990;28(6):588
panaxacol  106828-96-0   *Glycols *Diynes Panax. Chem Pharm Bull (Tokyo) 1990;38(6):1447
panaxydol chlorohydrin  111103-92-5   *Diynes. Arch Pharm (Weinheim) 1989;322(4):223
1-chloro-9,10-epoxy-4,6-heptadecadiyne-2,3-diol  114687-51-3   *Fatty Alcohols *Diynes Plant Extracts. Chem Pharm Bull (Tokyo) 1988;36(10):4206
1,8-heptadecadiene-4,6-diyne-3,10-diol  63910-76-9   *Fatty Alcohols *Diynes Panax. Planta Med 1988;54(2):183
panaxydol  72800-72-7   *Fatty Alcohols *Diynes. Arch Pharm (Weinheim) 1988;321(2):61
1,2-bis(10,12-tricosadiynoyl)phosphatidylcholine  76078-28-9   *Phosphatidylcholines *Diynes. Biophys J 1987;52(2):295
2-(4-acetoxy-3-chloro-1-butyn-1-yl)-5-(1,3-butadiyn-1-yl)thiophene  114691-31-5   *Thiophenes *Diynes. Planta Med 1986;(6):453
falcarindiol  55297-87-5 (9E)-heptadeca-1,9-dien-4,6-diyne-3,8-diol  *Fatty Alcohols *Diynes Araliaceae. Planta Med 1982;44(3):129
falcarinol  21852-80-2 1,9-heptadecadiene-4,6-diyn-3-ol  *Fatty Alcohols *Diynes Plant Extracts Toxins, Biological Apiaceae Araliaceae. J Agric Food Chem 26(6):1390;1978; J Chromatogr 161:271;1978; Yakugaku Zasshi 1981;101(12):1113
cicutoxin  505-75-9   *Fatty Alcohols *Diynes Toxins, Biological. Neurology 25(8):730;1975

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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