encyclopedia of medical concepts
ψ 
ψ 

Enediynes

More information in Books or onNLM PubMed
Definition: Compounds with triple bonds to each side of a double bond. Many of these are CYTOTOXINS and are researched for use as CYTOTOXIC ANTIBIOTICS.     
Examples Zinostatin 		Other names Enediyne Group
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
(N,N'-bis(quinolin-2-yl-methylidene)octa-4-ene-2,6-diyne-1,8-diamine)zinc(II) chloride  0   *Enediynes *Coordination Complexes Zinc. Int J Hyperthermia 2011;27(5):435-44
N,N'-bis(1-pyridyl-2-yl-methylidene)octa-4-ene-2,6-diyne-1,8-diamine  0   *Pyridines *Enediynes. Int J Hyperthermia 2011;27(5):435-44
heptadeca-1-ene-4,6-diyne-3,8,9,10-tetrol  0   *Enediynes. J Org Chem. 2011 Apr 1;76(7):2029-39
tetraethynylethene  0   *Enediynes. J Org Chem. 2006 Aug 4;71(16):5841-7
(Z)-2-(6-(thieanisyl-2-yl)hexa-3-en-1,5-diynyl)benzenamine  0   *Enediynes. Toxicol In Vitro 2007 Feb;21(1):90-8
2-(6-(2-thieanisyl)-3-hexen-1,5-diynyl)aniline  0   *Aniline Compounds *Enediynes. Mol Cell Biochem 2006 Nov;292(1-2):99-105
maduropeptin enediyne  0   *Enediynes.
calichemicin aryltetrasaccharide  0   *Aminoglycosides *Enediynes.
calicheamicin 1,2,-dimethyl hydrazine dichloride  0   *Aminoglycosides *Enediynes. Leuk Lymphoma 2005 Aug;46(8):1115-20
hu3S193-N-acetyl gamma calicheamicin dimethyl hydrazide  0   *Aminoglycosides *Antibodies, Monoclonal *Enediynes. Clin Cancer Res 2004 Jul 1;10(13):4538-49
calicheamicin enediyne  0   *Aminoglycosides *Enediynes. Org Lett. 2004 May 27;6(11):1801-4
calicheamicin dienone  0   *Aminoglycosides *Enediynes. Org Lett. 2004 May 27;6(11):1801-4
peyssonenyne B  0   *Fatty Acids, Unsaturated *Enediynes. J Nat Prod 2004 Jun;67(6):1010-3
peyssonenyne A  0   *Fatty Acids, Unsaturated *Enediynes. J Nat Prod 2004 Jun;67(6):1010-3
calicheamicin thetaII  0   *Aminoglycosides *Pyrimidines *Enediynes. Oncogene. 2003 Dec 11;22(57):9107-20
Shishijimicin A  0   *Carbolines *Disaccharides *Enediynes. J Am Chem Soc 2003 Feb 26;125(8):2044-5
Shishijimicin C  0   *Carbolines *Disaccharides *Enediynes. J Am Chem Soc 2003 Feb 26;125(8):2044-5
Shishijimicin B  0   *Carbolines *Disaccharides *Enediynes. J Am Chem Soc 2003 Feb 26;125(8):2044-5
gymnasterkoreaside A  0   *Enediynes. Chem Pharm Bull (Tokyo) 2002 May;50(5):685-7
gymnasterkoreaside B  0   *Enediynes. Chem Pharm Bull (Tokyo) 2002 May;50(5):685-7
1-O-feruloyl-tetradeca-4,6,12-triene-8,10-diyne  0   *Enediynes. Planta Med 2001 Jul;67(5):482-4
N1999-A2  0   *Epoxy Compounds *Naphthalenes *Enediynes. J Am Chem Soc 2001 Mar 28;123(12):2887-8
hCTMO1-calicheamicin  0   *Aminoglycosides *Antibodies, Monoclonal *Enediynes. Ann Oncol 2000 Jun;11(6);735-41
enediynone  0   *Pyrimidines *Enediynes. Org Lett 2000 Nov 30;2(24):3761-4
enediynol  0   *Pyrimidines *Enediynes. Org Lett 2000 Nov 30;2(24):3761-4
calicheamicin gamma(1)I aryltetrasaccharide  0   *Aminoglycosides *Oligosaccharides *Enediynes. Proc Natl Acad Sci U S A 1999 Sep 14;96(19):10643-8
calicheamicin gamma(1)I aryltrisaccharide  0   *Trisaccharides *Enediynes. Proc Natl Acad Sci U S A 1999 Sep 14;96(19):10643-8
calicheamicin theta(1)I  0   *Aminoglycosides *Enediynes. Cancer Res 1998 Jul 15;58(14):2925-8
9,17-octadecadien-12,14-diyne-1,16-diol  0   *Enediynes. Contact Dermatitis 1997 May;36(5):252-5
phenyl-9-hydroxy-9-methyl-10,2,10-(epoxymetheno)-2-benz(b)azacyclododeca-5-ene-3,7-diyne-1-carboxylate  0   *Epoxy Compounds *Enediynes. Chem Pharm Bull (Tokyo) 1997 Jan;45(1):125-33
1-(benzoyloxy)-2-cyclodecene-4,9-diyne-6,7,8-triol  0   *Benzoates *Enediynes. Bioorg Med Chem 1996 Jan;4(1):105-13
heptadeca-2,9-diene-4,6-diyne-1,8-diol  0   *Fatty Alcohols *Enediynes. J Nat Prod 1994 Aug;57(8):1178-82
esperamicin P  133978-90-2   *Aminoglycosides *Enediynes. J Nat Prod 1994 May;57(5):629-33
kedarcidin chromophore  143591-04-2 2-Naphthalenecarboxamide, N-(13-chloro-2,3,6,7-tetradehydro-10-((2,6-dideoxy-3-C-methyl-alpha-L-ribo-hexopyranosyl)oxy)-1a,9-dihydro-20-oxo-23-((2,4,6-trideoxy-4-(dimethylamino)-alpha-L-lyxo-hexopyranosyl)oxy)-9,5-(epoxy(5,2)pyridinopropanoxyethano)-1)  *Cycloparaffins *Naphthalenes *Enediynes. Proc Natl Acad Sci USA 1993 Apr 1;90(7):2822-6
maduropeptin C  134910-73-9   *Peptides *Enediynes. J Antiobiot (Tokyo) 1991 Apr;44(4):403-14
maduropeptin B  134910-72-8   *Peptides *Enediynes. J Antibiot (Tokyo) 1991 Apr;44(4):403-14
maduropeptin A2  134910-71-7   *Peptides *Enediynes. J Antibiot (Tokyo) 1991 Apr;44(4):403-14
maduropeptin A1  134910-70-6   *Peptides *Enediynes. J Antiobiot (Tokyo) 1991 Apr;44(4):403-14
calicheamicin T  142518-72-7   *Aminoglycosides *Enediynes. Proc Natl Acad Sci U S A 1992 May 15;89(10):4608-12
seselidiol  132075-01-5   *Enediynes. J Nat Prod 1990;53(4):932
esperamicin C  107453-55-4   *Aminoglycosides *Enediynes. Proc Natl Acad Sci USA 1989;86(20):7672
esperamicin D  107473-04-1   *Aminoglycosides *Enediynes. Proc Natl Acad Sci USA 1989;86(20):7672
dynemicin A  124412-57-3   *Anthraquinones *Enediynes.
Pharma Action Anti-Bacterial Agents ; Antibiotics, Antineoplastic 		J Antibiot (Tokyo) 1989;42(9):1449
C 1027  120177-69-7   *Aminoglycosides *Enediynes.
Pharma Action Antibiotics, Antineoplastic 		J Antibiot (Tokyo) 1988;41(11):1575
panaxytriol  87005-03-6   *Fatty Alcohols *Enediynes. Nippon Geka Gakkai Zasshi 1988;89(6):971
calicheamicin gamma(1)I  108212-75-5   *Aminoglycosides *Enediynes.
Pharma Action Antibiotics, Antineoplastic ; Mutagens 		Science 1988;240(4856):1198
esperamicin A1  99674-26-7   *Aminoglycosides *Enediynes.
Pharma Action Alkylating Agents ; Antibiotics, Antineoplastic 		Biochemistry 1997 Dec 2;36(48):14868-73
enanthotoxin  20311-78-8   *Fatty Alcohols *Enediynes Toxins, Biological Apiaceae. C R Acad Sci D (Paris) 24:1833;1978; Neurology 25(8):730;1975
diacetylatractylodiol  55078-26-7 5,11-Tridecadiene-7,9-diyne-1,3-diol, diacetate  *Enediynes. Chem Pharm Bull 22(8):1943;1974

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy