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Lymphotoxin alpha1, beta2 Heterotrimer

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Definition: A heterotrimer complex consisting of one molecule of LYMPHOTOXIN-ALPHA and two molecules of the LYMPHOTOXIN-BETA. It is anchored to the cell surface via the transmembrane domains of the lymphotoxin-beta component and has specificity for the LYMPHOTOXIN BETA RECEPTOR. The lymphotoxin alpha1, beta2 heterotrimer plays a role in regulating lymphoid ORGANOGENESIS and the differentiation of certain subsets of NATURAL KILLER CELLS.      Other names alphabeta Heterotrimer, Lymphotoxin; alpha1beta2, Lymphotoxin; Heterotrimer, Lymphotoxin alphabeta; Lymphotoxin alphabeta Heterotrimer; Lymphotoxin alphabeta; Lymphotoxin alpha1beta2

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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