Definition: A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Caspase 9 is activated during cell stress by mitochondria-derived proapoptotic factors and by CARD SIGNALING ADAPTOR PROTEINS such as APOPTOTIC PROTEASE-ACTIVATING FACTOR 1. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES.
Other names Procaspase 9; Pro Caspase 9; ICE Like Apoptotic Protease 6; ICE LAP6 Protein; Procaspase-9; Pro-Caspase-9; ICE-Like Apoptotic Protease 6; ICE-LAP6 Protein; Apoptotic Protease Activating Factor 3; Caspase-9
