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Caspase 12

More information in Books or onNLM PubMed
Definition: A long pro-domain caspase that contains a caspase recruitment domain in its pro-domain region. Caspase 12 is activated by pro-apoptotic factors that are released during cell stress and by CARD SIGNALING ADAPTOR PROTEINS. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES.      Other names 12, Caspase; Caspase-12
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
CASP12 protein, human  0   *Caspase 12.
Casp12 protein, rat  0   *Caspase 12.
Casp12 protein, mouse  0   *Caspase 12.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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