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CARD Signaling Adaptor Proteins

More information in Books or onNLM PubMed
Definition: A family of intracellular signaling adaptor proteins that contain caspase activation and recruitment domains. Proteins that contain this domain play a role in APOPTOSIS-related signal transduction by associating with other CARD domain-containing members and in activating INITIATOR CASPASES that contain CARD domains within their N-terminal pro-domain region.     
Examples Apoptotic Protease-Activating Factor 1; CRADD Signaling Adaptor Protein; Nod1 Signaling Adaptor Protein; Nod2 Signaling Adaptor Protein; Receptor-Interacting Protein Serine-Threonine Kinase 2 		Other names Caspase Activation and Recruitment Domain Signalin
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Card6 protein, mouse  0   *CARD Signaling Adaptor Proteins. Mol Cell Biol 2008 Mar;28(5):1541-52
CARD9 protein, human  0   *CARD Signaling Adaptor Proteins. Cancer 2005 Nov 1;104(9):1885-93
Card10 protein, mouse  0   *CARD Signaling Adaptor Proteins Membrane Proteins.
Card11 protein, mouse  0   *CARD Signaling Adaptor Proteins.
CARD6 protein, human  0   *CARD Signaling Adaptor Proteins. J Biol Chem 2003 Aug 22;278(34):31941-9
CARD8 protein, human  0   *Neoplasm Proteins *CARD Signaling Adaptor Proteins Apoptosis. FEBS Lett. 2002 Jun 19;521(1-3):165-9; J Biol Chem 2001 Aug 24;276(34):32220-9; J Biol Chem 2001 Nov 23;276(47):44069-77; J Biol Chem 2002 Apr 19;277(16):13952-8
NLRC4 protein, human  0   *Calcium-Binding Proteins *CARD Signaling Adaptor Proteins. Genomics 2001 Jul;75(1-3):77-83
CARD10 protein, human  0   *CARD Signaling Adaptor Proteins Membrane Proteins. J Biol Chem 2001 Jun 15;276(24):21405-9
CARD14 protein, human  EC 4.6.1.-   *Guanylate Cyclase *Membrane Proteins *CARD Signaling Adaptor Proteins. J Biol Chem 2001 Apr 13;276(15):11877-82
CARD11 protein, human  EC 4.6.1.2   *Guanylate Cyclase *CARD Signaling Adaptor Proteins. J Biol Chem 2001 Apr 13;276(15):11877-82

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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