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Plasma Membrane Calcium-Transporting ATPases

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Definition: Calcium-transporting ATPases found on the PLASMA MEMBRANE that catalyze the active transport of CALCIUM from the CYTOPLASM into the extracellular space. They play a role in maintaining a CALCIUM gradient across plasma membrane.      Other names PMCA2 Calcium-Transporting ATPase; Plasma Membrane Calcium Transporting ATPases; Plasma Membrane Calcium Transporting ATPase 4; Plasma Membrane Calcium Transporting ATPase 3; Plasma Membrane Calcium Transporting ATPase 2; Plasma Membrane Calcium Transporting ATPase 1; PMCA4 Calcium Transporting ATPase; PMCA3 Calcium Transporting ATPase; PMCA2 Calcium Transporting ATPase; PMCA1 Calcium Transporting ATPase; PMCA Calcium Transporting ATPases; Calcium-Transporting ATPases, PMCA; Calcium-Transporting ATPase, PMCA4; Calcium-Transporting ATPase, PMCA3; Calcium-Transporting ATPase, PMCA2; Calcium-Transporting ATPase, PMCA1; Calcium Transporting ATPases, Plasma Membrane; ATPase, PMCA4 Calcium-Transporting; ATPase, PMCA3 Calcium-Transporting; ATPase, PMCA2 Calcium-Transporting
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
Pmca1b protein, mouse  EC 3.6.3.8   *Plasma Membrane Calcium-Transporting ATPases. Nutrition 2010 Nov-Dec;26(11-12):1188-94
ATP2B4 protein, human  EC 3.6.1.8   *Plasma Membrane Calcium-Transporting ATPases. Biochem J 2005 Nov 1;391(Pt 3):687-92
ATP2B3 protein, human  EC 3.6.3.8   *Plasma Membrane Calcium-Transporting ATPases.
Atp2b2 protein, rat  EC 3.6.3.8   *Plasma Membrane Calcium-Transporting ATPases.
Atp2b2 protein, mouse  EC 3.6.3.8   *Plasma Membrane Calcium-Transporting ATPases Isoenzymes.
ATP2B2 protein, human  EC 3.6.3.8   *Plasma Membrane Calcium-Transporting ATPases.
Atp2b1 protein, rat  EC 3.6.3.8   *Plasma Membrane Calcium-Transporting ATPases.
Atp2b1 protein, mouse  EC 3.6.3.8   *Plasma Membrane Calcium-Transporting ATPases.
ATP2B1 protein, human  EC 3.6.3.8   *Plasma Membrane Calcium-Transporting ATPases.
PMC1 protein, S cerevisiae  EC 3.6.3.8   *Saccharomyces cerevisiae Proteins *Plasma Membrane Calcium-Transporting ATPases. J Cell Biol 1994 Feb;124(3):351-63

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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