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Epithelial Sodium Channel

More information in Books or onNLM PubMed
Definition: An AMILORIDE-sensitive sodium channel found on salt-reabsorbing EPITHELIAL CELLS that line the distal NEPHRON, the distal COLON; SALIVARY DUCTS; SWEAT GLANDS; and the LUNG. It plays a critical role in the control of sodium balance, BLOOD VOLUME, and BLOOD PRESSURE.      Other names gamma Subunit, SCNN1; delta Subunit, SCNN1; beta Subunit, SCNN1; alpha Subunit, SCNN1; Subunit, SCNN1 beta; Subunit, SCNN1 alpha; Sodium Channel, Epithelial; Epithelial Amiloride Sensitive Sodium Channel; Sodium Channel, Nonvoltage-gated 1 Protein, gamma ; Sodium Channel, Nonvoltage-gated 1 Protein, delta ; Sodium Channel, Nonvoltage-gated 1 Protein, beta S; Sodium Channel, Nonvoltage-gated 1 Protein, alpha ; SCNN1 gamma Subunit; SCNN1 delta Subunit; SCNN1 beta Subunit; SCNN1 alpha Subunit; Epithelial Sodium Channel, gamma Subunit; Epithelial Sodium Channel, delta Subunit; Epithelial Sodium Channel, beta Subunit; Epithelial Sodium Channel, alpha Subunit
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
PPK28 protein, Drosophila  0   *Drosophila Proteins *Epithelial Sodium Channel. Nature. 2010 May 6;465(7294):91-5
ACD-1 protein, C elegans  0   *Caenorhabditis elegans Proteins *Epithelial Sodium Channel. EMBO J 2008 Sep 17;27(18):2388-99
Scnn1g protein, rat  0   *Epithelial Sodium Channel.
Scnn1g protein, mouse  0   *Epithelial Sodium Channel.
SCNN1G protein, human  0   *Epithelial Sodium Channel.
SCNN1D protein, human  0   *Epithelial Sodium Channel.
Scnn1b protein, rat  0   *Epithelial Sodium Channel.
Scnn1b protein, mouse  0   *Epithelial Sodium Channel.
SCNN1B protein, human  0   *Epithelial Sodium Channel.
Scnn1a protein, mouse  0   *Epithelial Sodium Channel.
SCNN1A protein, human  0   *Epithelial Sodium Channel.
Scnn1a protein, rat  0   *Epithelial Sodium Channel. Biochem Biophys Res Commun 2001 Nov 2;288(3):727-35
degenerin epithelial sodium channels  0   *Nerve Tissue Proteins *Epithelial Sodium Channel. J Biol Chem 1996 May 3;271(18):10433-6

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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