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Interleukin-1beta

More information in Books or onNLM PubMed
Definition: An interleukin-1 subtype that is synthesized as an inactive membrane-bound pro-protein. Proteolytic processing of the precursor form by CASPASE 1 results in release of the active form of interleukin-1beta from the membrane.      Other names Interleukin 1beta; Interleukin 1 beta; Interleukin-1 beta; Catabolin; IL-1 beta
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2-benzyl-5-(4-chlorophenyl)-6-(4-(methylthio)phenyl)-2H-pyridazin-3-one  0   *Pyridazines *Sulfides Interleukin-1beta/antagonists & inhibitors. Eur J Pharm Biopharm 2010 Oct;76(2):215-21
canakinumab  0   *Antibodies, Monoclonal Interleukin-1beta/antagonists & inhibitors. N Engl J Med 2009 Jun 4;360(23):2416-25ILARIS
IL1B protein, human  0   *Interleukin-1beta.
interleukin-1beta (204-215)  0   *Peptide Fragments *Interleukin-1beta. Biochem J 1992 Mar 15;282(Pt 3):773-9
interleukin-1 beta, serine(71)  0   *Interleukin-1beta Recombinant Proteins. Cancer 1991;68(7):1520
interleukin-1beta, methionyl-glutamyl-alanyl-glutamine  121797-27-1   *Interleukin-1beta Recombinant Proteins. Biol Chem Hoppe Seyler 1990;371(1):23
interleukin 1beta (193-195)  117027-34-6   *Peptide Fragments *Interleukin-1beta. Nature 1988;334(6184):698
interleukin-1beta (163-171)  106021-96-9   *Interleukin-1beta *Peptide Fragments. J Immunol 1987;139(3):800

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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