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Adrenomedullin

More information in Books or onNLM PubMed
Definition: A 52-amino acid peptide with multi-functions. It was originally isolated from PHEOCHROMOCYTOMA and ADRENAL MEDULLA but is widely distributed throughout the body including lung and kidney tissues. Besides controlling fluid-electrolyte homeostasis, adrenomedullin is a potent vasodilator and can inhibit pituitary ACTH secretion.     
Pharmacological Action Antihypertensive Agents; Bronchodilator Agents; Cardiotonic Agents; Vasodilator Agents
Other names Proadrenomedullin N Terminal 20 Peptide; Proadrenomedullin N-Terminal 20 Peptide; Proadrenomedullin (1-20); PAMP(1-20)NH2; Adrenomedullin (1-52); ADM(1-52); ADM (1-52)
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
ADM protein, human  0   *Adrenomedullin.
intermedin protein, rat  0   *Neuropeptides *Adrenomedullin. Am J Physiol Regul Integr Comp Physiol 2005 Apr;288(4):R919-27
adrenomedullin (24-50), rat  0   *Peptide Fragments Adrenomedullin. Cell Mol Biol (Noisy-le-grand) 2003 Sep;49(6):939-43
adrenomedullin (20-50), rat  0   *Peptide Fragments *Adrenomedullin. Cell Mol Biol (Noisy-le-grand) 2003 Sep;49(6):939-43
adrenomedullin (11-26)  0   *Peptide Fragments *Adrenomedullin. Peptides 2001 Nov;22(11):1713-8
adrenomedullin (27-52)  0   *Peptide Fragments *Adrenomedullin. J Endocrinol 2001 Jul;170(1):251-7
adrenomedullin (1-50)  0   *Peptide Fragments *Adrenomedullin. Am J Physiol 1997 Aug;273(2 Pt 2):R716-24
adrenomedullin(16-31)  0   *Peptide Fragments *Adrenomedullin. Peptides 1997;18(1):133-6
adrenomedullin (22-52)  0   *Peptide Fragments *Adrenomedullin Receptors, Adrenomedullin/antagonists & inhibitors. Am J Physiol 1997 Jan;272(1 Pt 2):R234-42
adrenomedullin (15-22)  0   *Peptide Fragments *Adrenomedullin. Hypertension 1996 Dec;28(6):1041-6
adrenomedullin precursor (45-92)  0   *Protein Precursors *Adrenomedullin. Life Sci 1995 Jul 14;57(8):PL 87-90
adrenotensin  0   *Peptide Fragments *Adrenomedullin. Life Sci 1995 Jul 14;57(8):PL 87-90
adrenomedullin (13-52)  0   *Peptide Fragments *Adrenomedullin. Am J Physiol 1995 Jun;268(6 Pt 2):H2211-5
adrenomedullin (1-12)  0   *Peptide Fragments *Adrenomedullin. Am J Physiol 1995 Jun;268(6 Pt 2):H2211-5
proadrenomedullin  0   *Protein Precursors *Adrenomedullin. Biochem Biophys Res Commun 1994 Jul 29;202(2):1081-7
prodepin  155740-32-2   *Peptide Fragments *Adrenomedullin. Life Sci 1994;54(23):PL409-12

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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