Cytokine Receptor Common beta Subunit (definition)

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Cytokine Receptor Common beta Subunit

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Definition: A receptor subunit that is a shared component of the INTERLEUKIN-3 RECEPTOR; the INTERLEUKIN-5 RECEPTOR; and the GM-CSF RECEPTOR. High affinity receptor complexes are formed with each of these receptors when their respective alpha subunits are combined with this shared beta subunit.

Other names Receptor, CSF2RB; Interleukin 5 Receptor beta Subunit; Interleukin 3 Receptor beta Subunit; IL 5 Receptor beta Subunit; IL 3 Receptor beta Subunit; GM CSF Receptor beta Subunit; Antigen, CD131; betaC Interleukin Receptor Subunit; Receptors, Cytokine, Common beta Chain; Interleukin-3, 5, GM-CSF Receptor beta Subunit; GM-CSF, IL-3, IL-5 Receptor Common beta-Chain; Cytokine Receptor Common beta Chain; CSF2RB Receptor; CD131 Antigen; Interleukin-5 Receptor beta Subunit; Interleukin-3 Receptor beta Subunit; IL-5 Receptor beta Subunit; IL-3 Receptor beta Subunit; GM-CSF Receptor beta Subunit; CD131 Antigens

Substance	CAS Registry & name	Categories	Source	Drugs*
CSF2RB protein, human	0	*Cytokine Receptor Common beta Subunit.	Blood 1998 Nov 15;92(10):3636-46
Csf2rb1 protein, mouse	144715-98-0	*Cytokine Receptor Common beta Subunit.	J Biol Chem 1992;267(2):979

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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