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Syndecans

More information in Books or onNLM PubMed
Definition: A family of transmembrane glycoproteins that contain a short cytoplasmic domain, a single-span transmembrane domain, and an extracellular domain with heparin sulfate and CHONDROITIN SULFATE chains. Syndecans interact with a variety of heparin-binding INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS and may play a role in modulating cellular signaling during EMBRYONIC DEVELOPMENT, tumorigenesis, and angiogenesis.     
Examples Syndecan-1; Syndecan-2; Syndecan-3; Syndecan-4 		Other names Syndecan
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
syndecan protein, Drosophila  0   *Syndecans *Drosophila Proteins. Proc Natl Acad Sci U S A. 1994 Apr 12;91(8):3334-8.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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