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Thiazolidines

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Definition: Reduced (protonated) form of THIAZOLES. They can be oxidized to THIAZOLIDINEDIONES.     
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
2-octyl-4-isothiazolin-3-one  0   *Thiazolidines. Br J Pharmacol. 2009 Jul;157(6):974-83.
BMS 824  0   *Thiazolidines Alanine/*analogs & derivatives. Antimicrob Agents Chemother. 2011 Aug;55(8):3795-802.
Se-phenyl thiazolidine-4-carboselenoate  0   *Organoselenium Compounds *Thiazolidines. Eur J Pharmacol. 2011 Oct 1;668(1-2):169-76.
3-(4'-(4'-fluorophenyl)-6'-phenylpyrimidin-2'-yl)-2-phenylthiazolidin-4-one  0   *Pyrimidines *Thiazolidines. J Enzyme Inhib Med Chem 2011 Jun;26(3):422-9
KR 66222  0   *Thiazolidines Valine/*analogs & derivatives Dipeptidyl Peptidase 4. Xenobiotica 2011 Jun;41(6):445-55
KR 66223  0   *Thiazolidines Valine/*analogs & derivatives Dipeptidyl-Peptidase IV Inhibitors. J Pharm Biomed Anal 2011 Jul 15;55(5):1083-8
ONO-5334  0   *Thiazolidines Osteoporosis, Postmenopausal/drug therapy Cathepsin K/antagonists & inhibitors. J Bone Miner Res. 2011 Jun;26(6):1303-12
3-((4-(2-styrylphenoxy)butanoyl)-4-hydroxyprolyl)thiazolidine  0   *Thiazolidines Proline/*analogs & derivatives. Biochem Biophys Res Commun 2011 Jun 17;409(4):693-8
ITP 79  0   *Benzimidazoles *Thiazolidines. Mol Cancer Ther 2011 Apr;10(4):626-36
5-(5-(3-chloro-5-ethoxy-4-hydroxybenzylidene)-3-methyl-4-oxothiazolidin-2-ylideneamino)-2-chlorobenzoic acid  0   *Aminobenzoic Acids *Thiazolidines PPAR gamma/antagonists & inhibitors. J Steroid Biochem Mol Biol 2011 Apr;124(3-5):112-20
CG 301269  0   *Oxazoles *Thiazolidines PPAR alpha/agonists PPAR gamma/agonists. Diabetes 2011 Feb;60(2):496-506
latrunculol A  0   *Macrolides *Thiazolidines. Anal Bioanal chem 2010 Mar;396(5):1741-4
3-(2-aminoethyl)-5-(3-phenyl-propylidene)-thiazolidine-2,4-dione  0   *Thiazolidines. Bioorg Med Chem Lett. 2010 Aug 1;20(15):4526-30
thiadiazolo-thiazolidine-4-one  0   *Thiazolidines. Chem Pharm Bull (Tokyo). 2010;58(6):805-10
3-((5E)-4-oxo-5-((5-(4-sulfamoylphenyl)-2-furyl)methylene)-2-thioxo-thiazolidin-3-yl)propanoic acid  0   *Propionic Acids *Thiazolidines. J Pharmacol Exp Ther. 2010 Feb;332(2):446-54
2-(1,1'-biphenyl)-4-yl-N-(5-(1,1-dioxo-1lambda(6)-isothiazolidin-2-yl)-1H-indazol-3-yl)acetamide  0   *Indazoles *Thiazolidines. Chemotherapy 2009;55(5):353-62
3-(5-(4-oxo-2-thioxo-3-(3-trifluoromethylphenyl)thiazolidin-5-ylidenemethyl)furan-2-yl)benzoic acid  0   *Furans *Benzoic Acids *Thiazolidines. Biochem J. 2009 Oct 1;423(1):61-9
N-(3-(4,5-dihydro-1,3-thiazol-2-yl)-1,3-thiazolidin-2-ylidene)-5H-dibenzo(a,d)(7)annulen-5-amine  0   *Thiazolidines Receptors, Estrogen/antagonists & inhibitors. Mol Cancer Ther 2009 Mar;8(3):672-81
(5Z,E)-3-(2-(4-chlorophenyl)-2-oxoethyl)-5-(1H-indol-3-ylmethylene)-thiazolidine-2,4-dione  0   *Indoles *Thiazolidines. J Pharm Pharmacol. 2009 Mar;61(3):339-45
(2-(2-(2,4-dioxo-1,3-thiazolidin-3-yl)ethylamino)-2-oxoethyl) 2-(furan-2-carbonylamino)acetate  0   *Thiazolidines. Protein Sci 2008 Dec;17(12):2145-55
2-(2-oxothiazolidin-3-yl)-4,5-dihydrothiazolium  0   *Thiazolidines. Acta Crystallogr C 2008 Jul;64(Pt 7):o395-7
fantac  0   *Folic Acid *Thiazolidines Drug Combinations. Bull Environ Contam Toxicol 2008 May;80(5):403-6
ZK-thiazolidinone  0   *Aniline Compounds *Thiazolidines. Mol Biol Cell 2007 Oct;18(10):4024-36
2-isopropyl-3-(2-nitrobenzyl)-1,3-thiazolidin-4-one  0   *Thiazolidines. Acta Crystallogr C 2007 Jul;63(Pt 7):o411-4
2,5,5-trimethylthiazolidine-4-carboxylic acid  0   *Thiazolidines. Rapid Commun Mass Spectrom 2007;21(7):1221-9
thiazolidine-2-one 1,1-dioxide  0   *Oxides *Thiazolidines. Bioorg Med Chem Lett. 2007 Feb 15;17(4):879-83
thiazolidinonyl 2-thiobarbituric acid  0   *Barbiturates *Thiazolidines. Eur J Med Chem. 2006 Oct;41(10):1223-9
thiazolidinonyl 2-oxobarbituric acid  0   *Barbiturates *Thiazolidines. Eur J Med Chem. 2006 Oct;41(10):1223-9
BML 241  0   *Thiazolidines. Endocrinology 2006 Oct;147(10):4705-12
spiro(3H-indole-3,2'-thiazolidine)-3'(1,2,4-triazol-3-yl)-2,4'(1H)-dione  0   *Indoles *Spiro Compounds *Thiazolidines. Bioorg Med Chem 2006 Apr 1;14(7):2409-17
12-(3,5-dichloro-2,4,6-triazinyl)benzo(d)benzo(1',2'-6,5)isoindolo(1,2-b)(1,3)thiazolidine  0   *Thiazolidines *Isoindoles. Anal Sci. 2005 Sep;21(9):1121-4
WAY103  0   *Pyrazoles *Thiazolidines. J Allergy Clin Immunol 2005 Oct;116(4):812-9
5-(2,4-dihydroxybenzylidene)-2-(phenylimino)-1,3-thiazolidin  0   *Thiazolidines. Cancer Res. 2005 Jul 15;65(14):6380-7
fosthiazate  0   *Organophosphorus Compounds *Thiazolidines. J Agric Food Chem. 2004 Oct 6;52(20):6239-42
3-(5-thioxo-L-prolyl)-L-thiazolidine-4-carboxylic acid  0   *Dipeptides *Thiazolidines. Farmaco 2003 Sep;58(9):883-9
2-(4-(4-nitrobenzyloxy)benzyl)thiazolidine-4-carboxylic acid ethyl ester  0   *Benzyl Compounds *Thiazolidines. Mol Pharmacol. 2004 Jul;66(1):44-55
3-((3-trifluoromethyl)phenyl)-5-((3-carboxyphenyl)methylene)-2-thioxo-4-thiazolidinone  0   *Benzoic Acids *Thiazolidines. Gastroenterology 2004 Feb;126(2):511-9
(5-(4-(N-2-pyridyl)-(2S)-pyrrolidine-2-methoxyl)phenylmethylene(thiazolidine-2,4-dione, malic acid salt))  0   *Pyridines *Thiazolidines. J Pharmacol Exp Ther. 2003 Aug;306(2):763-71
2-(2,6-diethylanilino)thiazolidine  0   *Aniline Compounds *Thiazolidines. Pest Manag Sci 2002 Nov;58(11):1118-25
3,3'-(1,2-ethanediyl)bis(2-(4-methoxyphenyl)thiazolidin-4-one)  0   *Thiazolidines. Eur J Pharmacol 2002 Jul 12;448(1):71-80
N-(2-mercaptoethyl)-1,3-thiazolidine  0   *Thiazolidines. J Agric Food Chem 2002 Sep 11;50(19):5391-3
2-(2,2-bis(4-chlorophenyl)ethyl)-2-(4-chlorophenyl)thiazolidin-4-one  0   *Chlorobenzenes *Thiazolidines. Eur J Med Chem 2002 Jan;37(1):63-7
P32-98 compound  0   *Pentanoic Acids *Thiazolidines Dipeptidyl Peptidase 4/metabolism. Diabetes 2002 Apr;51(4):943-50
3,3'-(1,2-ethanediyl)-bis(2-aryl-4-thiazolidinone)  0   *Thiazolidines. Bioorg Med Chem Lett 2001 Nov 5;11(21):2791-4
RibCyst  0   *Sugar Alcohols *Thiazolidines. J Med Chem 2001 Aug 2;44(16):2661-6
FR 171113  0   *Benzamides *Thiazolidines Receptors, Thrombin/antagonists & inhibitors. Eur J Pharmacol 1999 Nov 19;384(2-3):197-202
6-((2-pyrrolidinylcarbonyl)amino)-6-benzyl-5-oxo-(5H)-pyrrolo(2,1-b)thiazolidine-3-carboxamide  0   *Pyrrolidines *Thiazolidines. J Med Chem 1999 Jul 29;42(15):2977-87
6-((2-pyrrolidinylcarbonyl)amino)-6-butyl-5-oxo-(5H)-pyrrolo(2,1-b)thiazolidine-3-carboxamide  0   *Pyrrolidines *Thiazolidines. J Med Chem 1999 Jul 29;42(15):2977-87
6-((2-pyrrolidinylcarbonyl)amino)-6-(2-methylpropyl)-5-oxo-(5H)-pyrrolo(2,1-b)thiazolidine-3-carboxamide  0   *Pyrrolidines *Thiazolidines. J Med Chem 1999 Jul 29;42(15):2977-87
GW0072  0   *Thiazolidines. Proc Natl Acad Sci USA 1999 May 25;96(11):6102-6
N-(2-methylbenzyl)-3-(2-hydroxy-3-(3-hydroxy-2-methylbenzoyl)amino-4-phenylbutanoyl)-5,5-dimethyl-1,3-thiazolidine-4-carboxamide  0   *Oligopeptides *Thiazolidines. J Med Chem 1999 May 20;42(10):1789-802
S 17092-1  0   *Indoles *Thiazolidines. Biochem Biophys Res Commun 1999 Apr 21;257(3):657-61
1-(2-pyrrolidinylcarbonyl)-5'-oxospiro(pyrrolidine-2,6'-thiazolidino(3,2-a)piperidine)-3'-carboxamide  0   *Spiro Compounds *Thiazolidines. J Med Chem 1999 Feb 25;42(4):628-37
YHI-1  0   *Naphthalenes *Thiazolidines Cysteine/analogs & derivatives. Antivir Chem Chemother 1998 Sep;9(5):423-30
3-indocyanine-green-acyl-1,3-thiazolidine-2-thione  0   *Thiazolidines Indocyanine Green/*analogs & derivatives. Bioorg Med Chem 1998 Nov;6(11):2179-84
5-((2,4-dioxo-5-thiazolidinyl)methyl)-2-methoxy-N-((4-(trifluoromethyl)phenyl)methyl)benzamide  213252-19-8   *Thiazolidines. Diabetes 1998 Dec;47(12):1841-7
CP 060  0   *Phenols *Thiazolidines. J Med Chem 1998 Oct 22;41(22):4309-16
ethyl N-(3-(2-fluoro-4-(thiazolidin-3-yl(imino)methyl)benzoyl)amino-2,2-dimethylpentanoyl)piperidine-4-acetate  0   *Benzamidines *Piperidines *Thiazolidines Platelet Glycoprotein GPIIb-IIIa Complex/antagonists & inhibitors. J Med Chem 1998 Jun 18;41(13):2345-60
L 644698  0   *Benzoates *Thiazolidines. Br J Pharmacol 1998 Apr;123(7):1317-24
tazofelone  136433-51-7   *Phenols *Thiazolidines. Drug Metab Dispos 1997 Dec;25(12):1383-8
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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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