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Leukemia, Large Granular Lymphocytic

More information in Books or onNLM PubMed
Definition: A spectrum of disorders characterized by clonal expansions of the peripheral blood LYMPHOCYTE populations known as large granular lymphocytes which contain abundant cytoplasm and azurophilic granules. Subtypes develop from either CD3-negative NATURAL KILLER CELLS or CD3-positive T-CELLS. The clinical course of both subtypes can vary from spontaneous regression to progressive, malignant disease.      Other names T-LGL Leukemias; T LGL Leukemia; T Cell Large Granular Lymphocytic Leukemia; T Cell Large Granular Lymphocyte Leukemia; NK-LGL Leukemias; NK LGL Leukemia; NK Cell Large Granular Lymphocytic Leukemia; Leukemias, T-LGL; Leukemias, NK-LGL; Leukemias, LGL; Leukemia, T LGL; Leukemia, T Cell Large Granular Lymphocytic; Leukemia, NK LGL; LGL Leukemias; T-LGL Leukemia; T-Cell Large Granular Lymphocyte Leukemia; NK-LGL Leukemia; NK-Cell Large Granular Lymphocytic Leukemia; Lymphoproliferative Disease of Large Granular Lymp; Lymphoproliferative Disease of Granular Lymphocyte

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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