encyclopedia of medical concepts
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Chemokine CXCL12
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Definition
: A CXC chemokine that is chemotactic for T-LYMPHOCYTES and MONOCYTES. It has specificity for CXCR4 RECEPTORS. Two isoforms of CXCL12 are produced by alternative mRNA splicing.
Other names
Stromal Cell Derived Factor 1beta; Stromal Cell Derived Factor 1alpha; Stromal Cell Derived Factor 1; SDF1 3'A; SDF 1beta; SDF 1alpha; Pre B Cell Growth Stimulating Factor; Growth-
Stimulating Factor, Pre-
B-
Cell; Chemokine, CXCL12; Cell-
Derived Factor-
1beta, Stromal; CXCL12, Chemokine; Stromal Cell-
Derived Factor-
1alpha; Stromal Cell-
Derived Factor 1; SDF1-
3'A; SDF-
1alpha; Pre-
B-
Cell Growth-
Stimulating Factor; SDF-
1beta; Stromal Cell-
Derived Factor-
1beta; CXCL12 Chemokine
Substance
CAS Registry & name
Categories
Source
Drugs
*
technetium 99m MAS3-
SDF-
1alpha
0
*Organotechnetium Compounds
*Chemokine CXCL12.
J Nucl Med 2008 Jun;49(6):963-9
Cxcl12 protein, mouse
0
*Chemokine CXCL12.
CXCL12 protein, human
0
*Chemokine CXCL12.
SDF-
1 protein, Xenopus
0
*Xenopus Proteins
*Chemokine CXCL12.
Biochem Biophys Res Commun 2002 Feb 15;291(1):2340-7
methionine stromal cell-
derived factor-
1beta
0
*Chemokine CXCL12.
J Virol 1999 Jun;73(6):4582-95