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Acetogenins

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Definition: Polyketides of up to a few dozen carbons in length, formed by chain extension of multiple PROPIONATES and oxygenated to form tetrahydrofuran and lactone rings along the length of the chain. They are found in ANNONACEAE and other PLANTS. Related compounds cyclize to MACROLIDES.      Other names Acetogenins, Annonaceous; Annonaceous Acetogenins; Acetogenin Compounds
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
mitregenin  0   *Acetogenins. Nat Prod Commun. 2010 Nov;5(11):1793-4
squamostanin-D  0   *Acetogenins. Fitoterapia. 2009 Apr;80(3):177-81
squamostanin-C  0   *Acetogenins. Fitoterapia. 2009 Apr;80(3):177-81
(2E,6Z)-9-hydroxy-4-hydroxymethyl-2,6-nonadiene  0   *Acetogenins. J Asian Nat Prod Res. 2009 Aug;11(8):704-9
(2E,6Z)-9,10-dihydroxy-4-hydroxymethyl-2,6-decadiene  0   *Acetogenins. J Asian Nat Prod Res. 2009 Aug;11(8):704-9
(2E,6Z)-8,9,10-trihydroxy-4-hydroxymethyl-2,6-decadiene  0   *Acetogenins. J Asian Nat Prod Res. 2009 Aug;11(8):704-9
squamostanin B  0   *Acetogenins. J Asian Nat Prod Res 2009;11(3):250-6
squamostanin A  0   *Acetogenins. J Asian Nat Prod Res 2009;11(3):250-6
tucupentol  0   *Acetogenins. Chem Biodivers. 2009 Mar;6(3):335-40
folianin B  0   *Acetogenins. Planta Med 2009 Jan;75(1):80-3
9-hydroxyfolianin  0   *Acetogenins. Planta Med 2009 Jan;75(1):80-3
22-epicalamistrin  0   *Acetogenins. J Nat Prod 2008 Jan;71(1):130-3
laurenmariallene  0   *Hydrocarbons, Brominated *Acetogenins. J Nat Prod 2007 Dec;70(12):1901-5
laurendecumenyne B  0   *Hydrocarbons, Brominated *Acetogenins. J Nat Prod 2007 Sep;70(9):1499-502
laurendecumenyne A  0   *Hydrocarbons, Brominated *Acetogenins. J Nat Prod 2007 Sep;70(9):1499-502
laurendecumallene B  0   *Hydrocarbons, Brominated *Acetogenins. J Nat Prod 2007 Sep;70(9):1499-502
laurendecumallene A  0   *Hydrocarbons, Brominated *Acetogenins. J Nat Prod 2007 Sep;70(9):1499-502
chamuvarinin  0   *Acetogenins. J Nat Prod 2004 Jun;67(6):1041-3
Q-acetogenin  0   *Acetogenins Ubiquinone/*analogs & derivatives. Bioorg Med Chem Lett. 2003 Jul 21;13(14):2385-8

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012

Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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