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Receptors, CCR4

More information in Books or onNLM PubMed
Definition: CCR receptors with specificity for CHEMOKINE CCL17 and CHEMOKINE CCL22. They are expressed at high levels in T-LYMPHOCYTES; MAST CELLS; DENDRITIC CELLS; and NK CELLS.      Other names Receptor, CCR4; Antigen, CD194; CD194 Antigen; CCR4 Receptor; CC Chemokine Receptors 4; CD194 Antigens; CCR4 Receptors; CC Chemokine Receptor 4; Antigens, CD194
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
5-((4-(4-(2-ethoxy-5-(trifluoromethyl)-2,3-dihydro-1H-inden-1-yl)-3-methylpiperazin-1-yl)-4-methylpiperidin-1-yl)carbonyl)-4,6-dimethylpyrimidine  0   *Piperazines *Pyrimidines Receptors, CCR4/antagonists & inhibitors. J Pharmacol Exp Ther 2011 Jul;338(1):228-39
2-(4-(2-(diethylamino)ethoxy)phenyl)-N-(2,4-difluorobenzyl)-5-fluoropyrimidin-4-amine  0   *Pyrimidines Receptors, CCR4/antagonists & inhibitors. Biol Pharm Bull 2010;33(6):1067-9
3-(2-(2-phenyl-4-(4-pyridin-4-ylbenzyl)morpholin-2-yl)ethyl)quinazoline-2,4(1H,3H)-dione  0   *Morpholines *Quinazolinones Receptors, CCR4/antagonists & inhibitors. Eur J Pharmacol 2009 Dec 10;624(1-3):38-44
6-cyclopropancarbonyl-4-(2,4-dichlorobenzylamino)-2-(4-(2-(piperidin-1-yl)ethyl)piperazin-1-yl)-7,8-dihydro-5H-pyrido(4,3-d)pyrimidine  0   *Pyridines *Pyrimidines Receptors, CCR4/antagonists & inhibitors. Pharmacology 2009;84(3):171-82
Ccr4 protein, rat  0   *Receptors, CCR4.
Ccr4 protein, mouse  0   *Receptors, CCR4.
CCR4 protein, human  0   *Receptors, CCR4.

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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