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INDEL Mutation

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Definition: A mutation named with the blend of insertion and deletion. It refers to a length difference between two ALLELES where it is unknowable if the difference was originally caused by a SEQUENCE INSERTION or by a SEQUENCE DELETION. If the number of nucleotides in the insertion/deletion is not divisible by three, and it occurs in a protein coding region, it is also a FRAMESHIFT MUTATION.      Other names Mutations, Insertion-Deletion; Mutations, INDEL; Mutation, Insertion-Deletion; Mutation, INDEL; Insertion-Deletion Mutations; Insertion Deletion Mutation; INDEL Mutations; Insertion-Deletion Mutation

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
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