encyclopedia of medical concepts
ψ 

Protein Phosphatase 1

More information in Books or onNLM PubMed
Definition: A eukayrotic protein serine-threonine phosphatase subtype that dephosphorylates a wide variety of cellular proteins. The enzyme is comprised of a catalytic subunit and regulatory subunit. Several isoforms of the protein phosphatase catalytic subunit exist due to the presence of multiple genes and the alternative splicing of their mRNAs. A large number of proteins have been shown to act as regulatory subunits for this enzyme. Many of the regulatory subunits have additional cellular functions.      Other names Protein Serine Threonine Phosphatase 1 beta; Protein Phosphatase 1G; Protein Phosphatase 1 gamma 2; Protein Phosphatase 1 alpha; Phosphoprotein Phosphatase 1 gamma 1; Phosphoprotein Phosphatase 1 delta; Phosphatase-1 delta, Phosphoprotein; Type 1 Serine Threonine Protein Phosphatase; Protein-Serine-Threonine Phosphatase 1 beta; Protein Serine-Threonine Phosphatase 1 beta; Protein Phosphatase-1G; Protein Phosphatase-1 gamma 2; Protein Phosphatase-1 alpha; Protein Phosphatase-1; Protein Phosphatase 1gamma; Protein Phosphatase 1C gamma; Protein Phosphatase 1C; Protein Phosphatase 1, Regulatory Subunit; Protein Phosphatase 1, Inhibitory Subunit; Protein Phosphatase 1, Catalytic Subunit, gamma2 I
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
PPP1R14D protein, rat  0   *Protein Phosphatase 1 Protein Subunits. Biochem J 2004 Jan 1;377(Pt 1):171-81
AtI-2 protein, Arabidopsis  EC 3.1.3.16   *Arabidopsis Proteins *Protein Phosphatase 1. Biochem J. 2011 Apr 1;435(1):73-83
INH3 protein, Arabidopsis  EC 3.1.3.16   *Arabidopsis Proteins *Protein Phosphatase 1 Protein Subunits. Plant Physiol 2009 May;150(1):144-56
Mbs85 protein, mouse  EC 3.1.3.16   *Protein Phosphatase 1 Protein Subunits. Proc Natl Acad Sci U S A 2009 May 5;106(18):7571-6
MBS85 protein, human  EC 3.1.3.16   *Protein Phosphatase 1 Protein Subunits. J Biol Chem 2001 Jun 15;276(24):21209-16
Ppp1r11 protein, mouse  0   *Protein Phosphatase 1.
PPP1CA protein, mouse  EC 3.1.3.16   *Protein Phosphatase 1 Protein Subunits. Carcinogenesis 2008 Mar;29(3):491-9
PPP1R18 protein, human  EC 3.1.3.16   *Protein Phosphatase 1. Biochem Biophys Res Commun 2007 May 11;356(3):594-8
PPP1CB protein, human  EC 3.1.3.16   *Protein Phosphatase 1.
PPP1CA protein, human  EC 3.1.3.16   *Protein Phosphatase 1.
Ppp1cc protein, rat  EC 3.1.3.16   *Protein Phosphatase 1.
Ppp1cc protein, mouse  EC 3.1.3.16   *Protein Phosphatase 1.
PPP1CC protein, human  EC 3.1.3.16   *Protein Phosphatase 1.
Ppp1r15a protein, mouse  EC 3.1.3.16   *Protein Phosphatase 1.
Ppp1r7 protein, rat  0   *Protein Phosphatase 1.
Ppp1r7 protein, mouse  0   *Protein Phosphatase 1.
PPP1R7 protein, human  0   *Protein Phosphatase 1.
Ppp1r12a protein, rat  EC 3.1.3.16   *Protein Phosphatase 1. FEBS Lett 1994 Dec 12;356(1):51-5
Ppp1r3b protein, mouse  EC 3.1.3.16   *Protein Phosphatase 1.
Ppp1r15b protein, mouse  EC 3.1.3.16   *Protein Phosphatase 1. J Cell Biol 2003 Nov 24;163(4):767-75
PPP1R14C protein, human  EC 3.1.3.16   *Protein Phosphatase 1. J Biol Chem 2002 Apr 12;277(15):13312-20
GIP1 protein, S cerevisiae  EC 3.1.3.16   *Saccharomyces cerevisiae Proteins *Protein Phosphatase 1. Mol Cell Biol 1996 Aug;16(8):4199-206
GLC7 protein, S cerevisiae  EC 3.1.3.16   *Saccharomyces cerevisiae Proteins *Protein Phosphatase 1. Mol Gen Genet 1995 Jan 20;246(2):212-22
PPP1R15A protein, human  EC 3.1.3.16   *Protein Phosphatase 1 DNA Damage. Proc Natl Acad Sci U S A 1994 Jun 7;91(12):5247-51
GAC1 protein, S cerevisiae  0   *Saccharomyces cerevisiae Proteins *Protein Phosphatase 1. EMBO J 1992 Jan;11(1):87-96
REG1 protein, S cerevisiae  EC 3.1.3.16   *Saccharomyces cerevisiae Proteins *Protein Phosphatase 1. Eur J Biochem 1991;200(2):311

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy