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Ribosome Inactivating Proteins, Type 2

More information in Books or onNLM PubMed
Definition: Ribosome inactivating proteins consisting of two polypeptide chains, the toxic A subunit and a lectin B subunit, linked by disulfide bridges. The lectin portion binds to cell surfaces and facilitates transport into the ENDOPLASMIC RETICULUM.     
Examples Abrin; Ricin; Shiga Toxins
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
ebulin 1 protein, Sambucus ebulus  0   *Ribosome Inactivating Proteins, Type 2. J Biol Chem 1993 Aug 25;268(24):18195-9
mistletoe lectin I  0   *Toxins, Biological *Ribosome Inactivating Proteins, Type 2.
aralin  0   *Ribosome Inactivating Proteins, Type 2 Plant Extracts. Planta Med. 2004 May;70(5):469-71
ribosome-inactivating protein, Cinnamonum camphora  0   *Ribosome Inactivating Proteins, Type 2.
ebulin r protein, Sambucus ebulus  0   *Ribosome Inactivating Proteins, Type 2. Cell Mol Biol (Noisy-le-grand) 1997 Jun;43(4):485-99
camphorin protein, Cinnamomum camphora  0   *Ribosome Inactivating Proteins, Type 2. Cell Biochem Funct 1996 Sep;14(3):157-61
ribosome-inactivating protein 2, maize  0   *Ribosome Inactivating Proteins, Type 2 N-Glycosyl Hydrolases. Plant Physiol 1995 Feb;107(2):661-2
Iris lectin  0   *Ribosome Inactivating Proteins, Type 2. J Biol Chem 1994 Mar 11;269(10):7666-73
Eranthis hyemalis lectin  0   *Ribosome Inactivating Proteins, Type 2. J Biol Chem 1993 Nov 25;268(33):25176-83
MAP30 protein, Momordica charantia  0   *Ribosome Inactivating Proteins, Type 2. FEBS Lett 1990;272(1-2):12
volkensin  91933-11-8 Volkensin  *Ribosome Inactivating Proteins, Type 2 Protein Synthesis Inhibitors. J Biol Chem 1985;260(27):14589
phytolaccin protein, Phytolacca americana  1339-33-9 Phytolaccin  *Ribosome Inactivating Proteins, Type 2 Ribosomes. Biochem Biophys Res Commun 1985;130(2):879
modeccin A-chain-ricin B-chain hybrid toxin  0   *Ricin *Ribosome Inactivating Proteins, Type 2 Toxins, Biological. Biochim Biophys Acta 1983;761(3):296
modeccin  65988-88-7   *Ribosome Inactivating Proteins, Type 2 Toxins, Biological. Biochem Biophys Res Commun 1979;90(2):648; Biochem J 174(2):491;1978; Biochem J 176(2):371;1978; Biochem J 178(1):233;1979; Biochim Biophys Acta 562(3):495;1979; Eur J Biochem 93(1):447;1979; Exp Cell Res 1980;24(2):321; FEBS Lett 85(1):65;1978; J Biol Chem 253(14):5069;1978; J Supramol Struct 9(1):15;1978
ribosome inactivating protein, Viscum  0   *Toxins, Biological *Plant Preparations *Ribosome Inactivating Proteins, Type 2.
Pharma Action Adjuvants, Immunologic 		Eur J Pharmacol 23(3):223;1973

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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