encyclopedia of medical concepts
ψ 
ψ 

Cathelicidins

More information in Books or onNLM PubMed
Definition: Antimicrobial cationic peptides with a highly conserved amino terminal cathelin-like domain and a more variable carboxy terminal domain. They are initially synthesized as preproproteins and then cleaved. They are expressed in many tissues of humans and localized to EPITHELIAL CELLS. They kill nonviral pathogens by forming pores in membranes.     
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
cathelicidin LL-37 (18-29), human  0   *Peptide Fragments *Cathelicidins. J Biol Chem 2008 Nov 21;283(47):32637-43
cathelicidin BF, Bungarus fasciatus  0   *Cathelicidins. PLoS ONE 2008;3(9):e3217
antimicrobial peptide LL-37  0   *Cathelicidins Adjuvants, Immunologic. J Am Acad Dermatol 2002 Sep;47(3):347-50
SMAP29 protein, Ovis aries  0   *Blood Proteins *Cathelicidins. FEBS Lett 1999 Dec 10;463(1-2):58-62
cathelicidin antimicrobial peptide  0   *Cathelicidins Anti-Bacterial Agents. FEBS Lett 1996 Aug 5;391(1-2):5-8; J Biol Chem 1997 May 16;272(20):13088-93

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy