encyclopedia of medical concepts
ψ 
ψ 

RING Finger Domains

More information in Books or onNLM PubMed
Definition: A zinc-binding domain defined by the sequence Cysteine-X2-Cysteine-X(9-39)-Cysteine-X(l-3)-His-X(2-3)-Cysteine-X2-Cysteine -X(4-48)-Cysteine-X2-Cysteine, where X is any amino acid. The RING finger motif binds two atoms of zinc, with each zinc atom ligated tetrahedrally by either four cysteines or three cysteines and a histidine. The motif also forms into a unitary structure with a central cross-brace region and is found in many proteins that are involved in protein-protein interactions. The acronym RING stands for Really Interesting New Gene.      Other names RING Finger Motif; RING Finger Domain; Domains, RING Finger; RING Finger Motifs
 
SubstanceCAS Registry & nameCategoriesSource
ubiquitin-conjugating enzyme 7-interacting protein 4, human  EC 6.3.2.19   *Carrier Proteins *Ubiquitin-Protein Ligases RING Finger Domains. J Biol Chem. 2012 Feb 17;287(8):5615-26.
RNF185 protein, human  EC 6.3.2.19   *Mitochondrial Proteins *Ubiquitin-Protein Ligases Membrane Proteins RING Finger Domains. PLoS One. 2011;6(9):e24367.
Gid9 protein, Saccharomyces cerevisiae  0   *Saccharomyces cerevisiae Proteins RING Finger Domains. FEBS Lett. 2011 Dec 15;585(24):3856-61
Qin protein, Drosophila  EC 6.3.2.19   *Drosophila Proteins *Ubiquitin-Protein Ligases RING Finger Domains. Mol Cell. 2011 Nov 18;44(4):572-84.
KF-1 protein, mouse  EC 6.3.2.19   *Ubiquitin-Protein Ligases RING Finger Domains. Cell Biochem Biophys 2011 Jun;60(1-2):69-75
TRIM-9 protein, C elegans  EC 6.3.2.19   *Caenorhabditis elegans Proteins *Ubiquitin-Protein Ligases RING Finger Domains. J Genet Genomics 2011 Jan;38(1):1-11
MSL2 protein, human  EC 6.3.2.19   *Ubiquitin-Protein Ligases RING Finger Domains. Mol Cell 2011 Jul 8;43(1):132-44
RNF152 protein, human  EC 6.3.2.19   *Ubiquitin-Protein Ligases RING Finger Domains. Protein Cell 2010 Jul;1(7):656-63
RNF213 protein, human  EC 6.3.2.19   *Ubiquitin-Protein Ligases Moyamoya Disease RING Finger Domains. J Hum Genet 2011 Jan;56(1):34-40
DAL2 protein, Arabidopsis  0   *Arabidopsis Proteins *Apoptosis Regulatory Proteins RING Finger Domains. Plant Cell Rep 2011 Jan;30(1):37-48
DAL1 protein, Arabidopsis  0   *Arabidopsis Proteins *Apoptosis Regulatory Proteins RING Finger Domains. Plant Cell Rep 2011 Jan;30(1):37-48
RING1b protein, Arabidopsis  0   *Carrier Proteins *Arabidopsis Proteins RING Finger Domains. Cell Res 2010 Decv;20(12):1332-44
RING1a protein, Arabidopsis  0   *Carrier Proteins *Arabidopsis Proteins RING Finger Domains. Cell Res 2010 Decv;20(12):1332-44
Lnx-2b protein, zebrafish  EC 6.3.2.19   *Zebrafish Proteins *Ubiquitin-Protein Ligases RING Finger Domains. Biochem Biophys Res Commun 2010 Nov 26;402(4):626-30
POSH2 protein, human  0   *Ubiquitin-Protein Ligases RING Finger Domains. FEBS Lett 2010 Sep 24;584(18):3867-72
RNF-121 protein, C elegans  EC 6.3.2.19   *Caenorhabditis elegans Proteins *Ubiquitin-Protein Ligases RING Finger Domains. Mol Biol Cell 2010 Jun;21(11):1788-98
neurodegeneration associated protein 1, rat  EC 6.3.2.19   *DNA-Binding Proteins *Ubiquitin-Protein Ligases Nerve Tissue Proteins RING Finger Domains. J Neurosci 1995 Jul;15(7 Pt 2):5238-48

To share this definition, click "text" (Facebook, Twitter) or "link" (blog, mail) then paste text link
Ads by Google

Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
This website is accredited by Health On the Net Foundation. Click to verify. We comply with the HONcode standard for trustworthy health information: verify here.
About Reference.MD Privacy