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Indolizidines

More information in Books or onNLM PubMed
Definition: Saturated indolizines that are fused six and five-membered rings with a nitrogen atom at the ring fusion. They are biosynthesized in PLANTS by cyclization of a LYSINE coupled to ACETYL COENZYME A. Many of them are naturally occurring ALKALOIDS.     
 
SubstanceCAS Registry & nameCategoriesSourceDrugs*
(13aS)-deoxytylophorinine  0   *Phenanthrolines *Indolizidines. Chemotherapy. 2011;57(4):310-20
flueggine B  0   *Indolizidines. Org Lett. 2011 Aug 5;13(15):3888-91
ent-cyclizidine  0   *Indolizidines Alkaloids. Org Lett. 2011 Mar 4;13(5):1048-51
steviamine  0   *Imino Sugars *Indolizidines. Org Lett. 2010 Jun 4;12(11):2562-5
3-butyl-5-propyl-8-hydroxyindolizidine  0   *Indolizidines Ant Venoms. Org Biomol Chem 2009 Nov 7;7(21):4491-5
prosopilosidine  0   *Indolizidines. J Nat Prod 2009 Jan;72(1):92-8
6-N-(2'-pyrrolidinylcarbonyl)amino-6-(2-methylpropyl)-8a-carboxamidoindolizidine-5-one  0   *Indolizidines Proline/*analogs & derivatives. J Med Chem 2007 Dec 27;50(26):6725-9

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Sources: NLM Medical Subject Headings, NIH UMLS, Drugs@FDA, FDA AERS original data copyright United States Government. No endorsement implied. Last modified 6/6/2012
Warning: the drugs or drug combinations referred to here may be similar or related, but are not be the same ones and may not have the same pharmacological action as other substances described on the same page or in the same row. Please refer to product monograph or to your doctor
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