encyclopedia of medical concepts
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Primary Myelofibrosis
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Definition
: A de novo myeloproliferation arising from an abnormal stem cell. It is characterized by the replacement of bone marrow by fibrous tissue, a process that is mediated by CYTOKINES arising from the abnormal clone.
Other names
Primary Myelofibroses; Nonleukemic Myelosis; Nonleukemic Myeloses; Myeloses, Nonleukemic; Myeloscleroses; Myeloid Metaplasias, Agnogenic; Myeloid Metaplasias; Myeloid Metaplasia, Agnogenic; Myelofibrosis, Primary; Myelofibroses, Primary; Myelofibroses; Metaplasias, Myeloid; Metaplasias, Agnogenic Myeloid; Metaplasia, Myeloid; Metaplasia, Agnogenic Myeloid; Fibroses, Bone Marrow; Bone Marrow Fibroses; Agnogenic Myeloid Metaplasias; Myelosis, Nonleukemic; Myelosclerosis
Substance
CAS Registry & name
Categories
Source
Panostotic fibrous dysplasia
0
*Bone Diseases, Metabolic
*Fibrous Dysplasia of Bone
*Primary Myelofibrosis.
Familial myelofibrosis
0
*Primary Myelofibrosis.
